Evidence map›Paper›PMID 28807144›Full record

ArticleCell calcium2017

Regulation of L-type Ca

Alejandro Sandoval, Paz Duran, María A Gandini, Arturo Andrade, Angélica Almanza, Simon Kaja, Ricardo Felix

Abstract read
In one paragraph

Article in Cell calcium, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. The Leucine-Rich Repeat Kinase 2 Variant LRRK2International journal of molecular sciences · 2025
    Article
  5. Article
  6. The Glucagon-Like Adipokinetic Hormone inFrontiers in physiology · 2021
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Alejandro SandovalFES Iztacala UNAM, Tlalnepantla De Baz, Mexico.
Paz DuranDepartamento de Biología Celular, Cinvestav-IPN, Ciudad de México, Mexico.
María A GandiniHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Arturo AndradeDepartment of Biological Sciences, University of New Hampshire, Durham, NH, USA.
Angélica AlmanzaDirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría, Ramón de la Fuente Muñiz, Ciudad de México, Mexico.
Simon KajaDepartment of Ophtalmology and Molecular Pharmacology & Therapeutics, Loyola University, Chicago, Strich School of Medicine, Maywood, IL, USA.
Ricardo FelixDepartamento de Biología Celular, Cinvestav-IPN, Ciudad de México, Mexico. Electronic address: rfelix@cinvestav.mx.
Instituto Politécnico Nacional · MXInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXLoyola University Chicago · USUniversity of Calgary · CAUniversity of New Hampshire · US

Funding

Role of Gi/o-Protein Inhibition of CaV2.2 Channels in Anxiety BehaviorR00MH099405 · NIMH · UNIVERSITY OF NEW HAMPSHIRE · PI ANDRADE, ARTURO · 2015 to 2017
$738k
NIMH NIH HHS R00 MH099405
6 · The paper itself

Abstract

cGMP is a second messenger widely used in the nervous system and other tissues. One of the major effectors for cGMP is the serine/threonine protein kinase, cGMP-dependent protein kinase (PKG), which catalyzes the phosphorylation of a variety of proteins including ion channels. Previously, it has been shown that the cGMP-PKG signaling pathway inhibits Ca

Indexed as

Signal TransductionAnimalsCalcium Channels, L-TypeCarbazolesCell LineCyclic GMPCyclic GMP-Dependent Protein KinasesHEK293 CellsHumansInsulinMembrane PotentialsMutagenesis, Site-DirectedNitric OxidePatch-Clamp TechniquesPhosphorylationProtein Subunits8-bromocyclic GMPCalcium Channels, L-TypeCarbazolesCyclic GMPCyclic GMP-Dependent Protein KinasesInsulinKT 5823Nitric OxideProtein SubunitsCav channelscGMPInsulinL-type channelsPKGRin-m5F cells

Identifiers

PMID28807144
PMCPMC5776030
OpenAlexW2614140443

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.