Evidence map›Paper›PMID 28807143›Full record

SynthesisGeneral hospital psychiatry2017

Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: A systematic review and meta-analysis.

John A Naslund, Karen L Whiteman, Gregory J McHugo, Kelly A Aschbrenner, Lisa A Marsch, Stephen J Bartels

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in General hospital psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  3. EPA guidance on lifestyle interventions for adults with severe mental illness: A meta-review of the evidence.European psychiatry : the journal of the Association of European Psychiatrists · 2024
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John A NaslundThe Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, NH, United States; Health Promotion Research Center at Dartmouth, Lebanon, NH, United States. Electronic address: john.a.naslund@gmail.com.
Karen L WhitemanHealth Promotion Research Center at Dartmouth, Lebanon, NH, United States.
Gregory J McHugoDepartment of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Kelly A AschbrennerHealth Promotion Research Center at Dartmouth, Lebanon, NH, United States; Department of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Lisa A MarschDepartment of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States; Center for Technology and Behavioral Health, Dartmouth College, Lebanon, NH, United States.
Stephen J BartelsThe Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, NH, United States; Health Promotion Research Center at Dartmouth, Lebanon, NH, United States; Department of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States; Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.

Funding

Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Training Geriatric Mental Health Services ResearchersT32MH073553 · NIMH · DARTMOUTH-HITCHCOCK CLINIC · PI BRUCE, MARTHA L · 2005 to 2019
$6.4M
Health Promotion and Disease Prevention Research CenterU48DP005018 · DP · DARTMOUTH COLLEGE · PI ADACHI-MEJIA, ANNA MARIA · 2014 to 2018
$5.6M
Health Promotion and Fitness for Younger and Older Adults With SMIR01MH078052 · NIMH · DARTMOUTH COLLEGE · PI BARTELS, STEPHEN J · 2007 to 2012
$3.5M
Statewide Intervention to Reduce Early Mortality in Persons with Mental IllnessR01MH089811 · NIMH · DARTMOUTH COLLEGE · PI BARTELS, STEPHEN J · 2010 to 2014
$2.7M
REDUCING DISPARITIES IN HEALTH FOR VULNERABLE POPULATIONS IN NH & VT (CATEGORY 2)U48DP001935 · DP · DARTMOUTH COLLEGE · PI FISHER, ELLIOTT S · 2009 to 2013
$2.3M
Promoting Health & Functioning in Persons with SMIR01DD000140 · DD · DARTMOUTH COLLEGE · PI BARTELS, STEPHEN J · 2006 to 2008
$975k
ACL HHS U48DP005018NCBDD CDC HHS R01 DD000140NCCDPHP CDC HHS U48 DP001935NCCDPHP CDC HHS U48 DP005018NIDA NIH HHS P30 DA029926NIMH NIH HHS R01 MH078052NIMH NIH HHS R01 MH089811NIMH NIH HHS T32 MH073553
6 · The paper itself

Abstract

objectiveTo conduct a systematic review and meta-analysis to estimate effects of lifestyle intervention participation on weight reduction among overweight and obese adults with serious mental illness.

methodWe systematically searched electronic databases for randomized controlled trials comparing lifestyle interventions with other interventions or usual care controls in overweight and obese adults with serious mental illness, including schizophrenia spectrum or mood disorders. Included studies reported change in weight [kg] or body mass index (BMI) [kg/m

resultsSeventeen studies met inclusion criteria (1968 participants; 50% male; 66% schizophrenia spectrum disorders). Studies were grouped by intervention duration (≤6-months or ≥12-months). Lifestyle interventions of ≤6-months duration showed greater weight reduction compared with controls as indicated by effect size for weight change from baseline (SMD=-0.20; 95% CI=-0.34, -0.05; 10 studies), but high statistical heterogeneity (I

conclusionLifestyle interventions appear effective for treating overweight and obesity among people with serious mental illness. Interventions of ≥12-months duration compared to ≤6-months duration appear to achieve more consistent outcomes, though effect sizes are similar for both shorter and longer duration interventions.

Indexed as

ComorbidityMental DisordersRisk Reduction BehaviorWeight LossHumansOutcome and Process Assessment, Health CareOverweightBipolar disorderLifestyle interventionMental illnessObesitySchizophreniaWeight loss

Identifiers

PMID28807143
PMCPMC5575752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.