Evidence map›Paper›PMID 28806932›Full record

ArticleBMC medical research methodology2017

The impact of the lookback period and definition of confirmatory events on the identification of incident cancer cases in administrative data.

Jonas Czwikla, Kathrin Jobski, Tania Schink

Open access · goldAbstract read
In one paragraph

Article in BMC medical research methodology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 60 citations in OpenAlex.

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  3. Prognostic impact of disease-related complications in asymptomatic mitral regurgitation: a health insurance claims analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jonas CzwiklaDepartment of Health, Long-term Care and Pensions, SOCIUM Research Center on Inequality and Social Policy, University of Bremen, P.O. Box 33 04 40, 28334, Bremen, Germany. czwikla@uni-bremen.de.ORCID http://orcid.org/0000-0002-1171-4717
Kathrin JobskiDepartment of Health Services Research, Carl von Ossietzky University of Oldenburg, P.O. Box 2503, 26111, Oldenburg, Germany.
Tania SchinkLeibniz Institute for Prevention Research and Epidemiology - BIPS, Drug Safety Unit, Achterstrasse 30, 28359, Bremen, Germany.
Carl von Ossietzky Universität Oldenburg · DELeibniz Institute for Prevention Research and Epidemiology - BIPS · DEUniversity of Bremen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis cohort study examined the impact of the lengths of lookback and confirmation periods as well as the definition of confirmatory events on the number of incident cancer cases identified and age-standardized cumulative incidences (ACI) estimated in administrative data using German cancer registry data as a benchmark.

methodsACI per 100,000 insured persons for breast, prostate and colorectal cancer were estimated using BARMER Statutory Health Insurance claims data. Incident cancer cases were defined as having an in- or outpatient diagnosis in 2013, no diagnosis in a lookback period of 1 year and a second diagnosis (or death) in a confirmation period of 1 quarter. We varied lookback periods from 1 to 7 years, confirmation periods from 1 to 4 quarters as well as the definition of confirmatory events and compared ACI estimates to cancer registry data.

resultsACI were higher for breast (138.7) and prostate (103.6) but lower for colorectal cancer (42.1) when compared to cancer registries (119.3, 98.0 and 45.5, respectively). Extending the lookback period to 7 years reduced ACI to 129.0, 95.1 and 38.3. An extended confirmation period of 4 quarters increased ACI to 151.3, 114.9 and 46.8. Including breast and colorectal surgeries as a confirmatory event reduced ACI to 114.9 and 37.1, respectively.

conclusionsThe choice of lookback and confirmation periods and the definition of confirmatory events have considerable impact on the number of incident cancer cases identified and ACI estimated. Researchers need to be aware of potential misclassification when identifying incident cancer cases in administrative data. Further validation studies as well as studies using administrative data to estimate cancer incidences should consider several choices of the lookback and confirmation periods and the definition of confirmatory events to show how these parameters impact the validity and robustness of their results.

Indexed as

RegistriesAlgorithmsBreast NeoplasmsCohort StudiesColorectal NeoplasmsFemaleHumansIncidenceMaleMiddle AgedProstatic NeoplasmsAdministrative claimsBreast neoplasmsColorectal neoplasmsEpidemiologyHealth services researchIncidenceInternational classification of diseasesNeoplasmsProstatic neoplasmsValidation

Identifiers

PMID28806932
PMCPMC5556662
OpenAlexW2749889369

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.