ArticleBMC genomics2017
Genome-wide comparative analysis of DNA methylation between soybean cytoplasmic male-sterile line NJCMS5A and its maintainer NJCMS5B.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- The Effects of DNA Methylation on Cytoplasmic Male Sterility in Sugar Beet.International journal of molecular sciences · 2024Article
- Reprogramming of DNA methylation and changes of gene expression in graftedFrontiers in plant science · 2024Article
- Integrated transcriptomic and proteomic analysis of a cytoplasmic male sterility line and associated maintainer line in soybean.Frontiers in plant science · 2023Article
- Epigenetic Dynamics and Regulation of Plant Male Reproduction.International journal of molecular sciences · 2022Review
- Evolutionary fates of gene-body methylation and its divergent association with gene expression in pigeonpea.The plant genome · 2022Article
- Integrated methylome and transcriptome analysis unravel the cold tolerance mechanism in winter rapeseed(Brassica napus L.).BMC plant biology · 2022Article
- Integrated Methylome and Transcriptome Analysis Provides Insights into the DNA Methylation Underlying the Mechanism of Cytoplasmic Male Sterility in Kenaf (International journal of molecular sciences · 2022Article
- Integrated Methylome and Transcriptome Analysis Widen the Knowledge of Cytoplasmic Male Sterility in Cotton (Frontiers in plant science · 2022Article
- Genome-wide identification of PME genes, evolution and expression analyses in soybean (Glycine max L.).BMC plant biology · 2021Article
- Transcriptome sequencing and metabolome analysis of food habits domestication from live prey fish to artificial diets in mandarin fish (Siniperca chuatsi).BMC genomics · 2021Article
- Differential DNA Methylation and Gene Expression Between ALV-J-Positive and ALV-J-Negative Chickens.Frontiers in veterinary science · 2021Article
- Genome-Wide DNA Methylation and Transcriptome Analyses Reveal Epigenetic and Genetic Mechanisms Underlying Sex Maintenance of Adult Chinese Alligator.Frontiers in genetics · 2021Article
- Chicken cecal DNA methylome alteration in the response to Salmonella enterica serovar Enteritidis inoculation.BMC genomics · 2020Article
- Comparative analysis of the transcriptome, methylome, and metabolome during pollen abortion of a seedless citrus mutant.Plant molecular biology · 2020Article
- Cytoplasm Types Affect DNA Methylation among Different Cytoplasmic Male Sterility Lines and Their Maintainer Line in Soybean (Plants (Basel, Switzerland) · 2020Article
- Article
- Analysis of longissimus muscle quality characteristics and associations with DNA methylation status in cattle.Genes & genomics · 2019Article
- Towards Exploitation of Adaptive Traits for Climate-Resilient Smart Pulses.International journal of molecular sciences · 2019Review
- Metabolomics Studies on Cytoplasmic Male Sterility during Flower Bud Development in Soybean.International journal of molecular sciences · 2019Article
- Abnormal tapetum development and energy metabolism associated with sterility in SaNa-1A CMS of Brassica napus L.Plant cell reports · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDNA methylation is an important epigenetic modification. It can regulate the expression of many key genes without changing the primary structure of the genomic DNA, and plays a vital role in the growth and development of the organism. The genome-wide DNA methylation profile of the cytoplasmic male sterile (CMS) line in soybean has not been reported so far.
resultsIn this study, genome-wide comparative analysis of DNA methylation between soybean CMS line NJCMS5A and its maintainer NJCMS5B was conducted by whole-genome bisulfite sequencing. The results showed 3527 differentially methylated regions (DMRs) and 485 differentially methylated genes (DMGs), including 353 high-credible methylated genes, 56 methylated genes coding unknown protein and 76 novel methylated genes with no known function were identified. Among them, 25 DMRs were further validated that the genome-wide DNA methylation data were reliable through bisulfite treatment, and 9 DMRs were confirmed the relationship between DNA methylation and gene expression by qRT-PCR. Finally, 8 key DMGs possibly associated with soybean CMS were identified.
conclusionsGenome-wide DNA methylation profile of the soybean CMS line NJCMS5A and its maintainer NJCMS5B was obtained for the first time. Several specific DMGs which participated in pollen and flower development were further identified to be probably associated with soybean CMS. This study will contribute to further understanding of the molecular mechanism behind soybean CMS.
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