ArticleAmerican journal of perinatology2018
The Oxytocin Product Correlates with Total Oxytocin Received during Labor: A Research Methods Study.
Article in American journal of perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Oxytocin treatment at birth accelerates an epigenetic shift in the oxytocin receptor gene in the maternal brain.BMC pregnancy and childbirth · 2025Article
- Maternal oxytocin treatment at birth increases epigenetic age in male offspring.Developmental psychobiology · 2024Article
- Article
- Neuroanatomical and functional consequences of oxytocin treatment at birth in prairie voles.Psychoneuroendocrinology · 2023Article
- Naturally Occurring Genetic Variants in the Oxytocin Receptor Alter Receptor Signaling Profiles.ACS pharmacology & translational science · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveTotal dose of oxytocin received during labor is an important variable in studies of human labor but is difficult to calculate. We sought to identify a surrogate measure for total dose of oxytocin received. STUDY
designFor each subject receiving oxytocin during labor, the oxytocin total dose received in labor was calculated as the area under the curve. Maximal oxytocin infusion rate, total duration of oxytocin infusion, and the product of both, defined as the oxytocin product, were then each correlated with the total dose of oxytocin received using the Pearson's correlation coefficient.
resultsOxytocin dosing data were available from 402 women at Duke and 6,907 women from Pithagore6. The two variables alone, or combined as the oxytocin product, demonstrated a high correlation with the oxytocin total dose (
conclusionThe oxytocin product, composed of two easily obtained variables, demonstrated a very high correlation with total oxytocin dose received in labor and represents a simple and accurate surrogate for total dose of oxytocin received during labor. The oxytocin product can be used in clinical studies in which oxytocin dose is an important variable.
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