Evidence map›Paper›PMID 28806778›Full record

ArticlePloS one2017

Serum resistin as an independent marker of aortic stiffness in patients with coronary artery disease.

Ji-Hung Wang, Chung-Jen Lee, Chiu-Fen Yang, Yu-Chih Chen, Bang-Gee Hsu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. Review
  6. Adipokines and Arterial Stiffness in Obesity.Medicina (Kaunas, Lithuania) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ji-Hung WangDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Chung-Jen LeeDepartment of Nursing, Tzu Chi University of Science and Technology, Hualien, Taiwan.
Chiu-Fen YangDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Yu-Chih ChenDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Bang-Gee HsuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.ORCID http://orcid.org/0000-0001-9364-4558
Tzu Chi University · TWBuddhist Tzu Chi General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubjects with higher carotid-femoral pulse wave velocity (cfPWV) will be at an increased risk for cardiovascular (CV) events in future. Resistin is an inflammatory mediator and a biomarker of CV diseases. We evaluated the association between serum resistin and aortic stiffness in patients with coronary artery disease (CAD).

methodsA total of 104 patients with CAD were enrolled in this study. cfPWV was measured using the SphygmoCor system. Patients with cfPWV >10 m/s were defined as the high aortic stiffness group.

resultsThirty-seven patients (35.6%) had high aortic stiffness and higher percentages of diabetes (p = 0.001), were of older age (p = 0.001) and had higher waist circumference (p < 0.001), systolic blood pressure (p = 0.027), pulse pressure (p = 0.013), high-sensitivity C-reactive protein (p < 0.001) and resistin levels (p < 0.001) but lower estimated glomerular filtration rate (p = 0.009) compared to subjects with low aortic stiffness. After adjusting for factors significantly associated with aortic stiffness by multivariate logistic regression analysis, serum resistin (odds ratio = 1.275, 95% confidence interval: 1.065-1.527, p = 0.008) was also found to be an independent predictor of aortic stiffness in patients with CAD.

conclusionsSerum resistin level is a biomarker for aortic stiffness in patients with CAD.

Indexed as

Vascular StiffnessAgedBiomarkersCoronary Artery DiseaseFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisResistinBiomarkersResistinRETN protein, human

Identifiers

PMID28806778
PMCPMC5555662
OpenAlexW2750223657

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.