ReviewCurrent opinion in ophthalmology2017
Tubulointerstitial nephritis and uveitis.
Review in Current opinion in ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 57 citations in OpenAlex.
- Tubulointerstitial nephritis and uveitis syndrome in a patient with diabetic nephropathy: a case report and literature review.Frontiers in medicine · 2026Article
- Clinical Presentation and Management of Tubulointerstitial Nephritis and Uveitis Syndrome: A Case Series.Cureus · 2026Article
- Tubulointerstitial nephritis and uveitis syndrome: an unexpected diagnosis.BMJ case reports · 2025Article
- Successful long-term treatment of tubulointerstitial nephritis and uveitis with mycophenolate.BMJ case reports · 2025Article
- Clinical outcomes in paediatric tubulointerstitial nephritis and uveitis syndrome (TINU).Eye (London, England) · 2024Article
- Mimickers of anterior uveitis, scleritis and misdiagnoses- tips and tricks for the cornea specialist.Journal of ophthalmic inflammation and infection · 2024Review
- Ocular manifestations and clinical outcomes in Tubulointerstitial Nephritis and Uveitis Syndrome (TINU).Eye (London, England) · 2024Article
- TINU: A Multisystemic Inflammatory Disorder-Case Report and Literature Review.Case reports in nephrology · 2024Article
- Ocular images-based artificial intelligence on systemic diseases.Biomedical engineering online · 2023Review
- Diagnostic and Management Strategies of Tubulointerstitial Nephritis and Uveitis Syndrome (TINU): Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Pediatric uveitis: Role of the pediatrician.Frontiers in pediatrics · 2022Review
- Tubulointerstitial nephritis and uveitis syndrome in an adolescent female: a case report.Journal of medical case reports · 2021Article
- Long-term clinical characteristics and renal prognosis of children with tubulointerstitial nephritis and uveitis syndrome.Pediatric nephrology (Berlin, Germany) · 2021Observational
- Tubulointerstitial Nephritis and Uveitis Syndrome: Case Series and Literature Review.Case reports in ophthalmological medicine · 2021Article
- Tubulointerstitial nephritis and uveitis: The first report from the ophthalmology perspective in India.Indian journal of ophthalmology · 2020Article
- Long-term Treatment Outcome of Tubulo-interstitial Nephritis and Uveitis Syndrome Associated Panuveitis with Steroid and Mycophenolate Mofetil.Korean journal of ophthalmology : KJO · 2020Article
- The genetic contribution ofAnnals of translational medicine · 2019Article
- A 36-Year-Old Man With Renal Failure, Fever, and Hypocomplementemia.Arthritis care & research · 2019Article
- Treatment challenges in an atypical presentation of tubulointerstitial nephritis and uveitis (TINU).American journal of ophthalmology case reports · 2018Article
- Clinical and Genetic Features of Tubulointerstitial Nephritis and Uveitis Syndrome with Long-Term Follow-Up.Journal of ophthalmology · 2018Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewTubulointerstitial nephritis and uveitis (TINU) is an important yet underrecognized ocular inflammatory syndrome. This review summarizes key historical publications that identified and defined the syndrome, and more recent literature that reveal the importance of urinary β2-microglobulin testing and kidney biopsy in the diagnostic evaluation of patients with TINU. Additionally, research studies providing new insights into disease pathogenesis are highlighted. RECENT
findingsIn contrast with initial reports of TINU manifesting exclusively as an anterior uveitis in pediatric patients, more recent reports have identified TINU in patients of all ages with a wide range of ocular manifestations. Urinary β2-microglobulin has emerged as a sensitive and specific laboratory screening test, and the role of kidney biopsy in differentiating TINU from sarcoidosis continues to evolve. Genetic studies have identified HLA-DQA101, HLA-DQB105, and HLA-DRB101 as high-risk alleles and the identification of antimonomeric C-reactive protein antibodies suggests a role for humoral immunity in disease pathogenesis. Management strategies have evolved to include systemic anti-inflammatory treatment as a result of important outcome studies in patients with significant renal and ocular disease. SUMMARY: With greater recognition, understanding, and treatment of this syndrome, both ocular inflammation and renal disease can be better addressed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.