Evidence map›Paper›PMID 28806173›Full record

ArticleeLife2017

The β-alanine transporter BalaT is required for visual neurotransmission in

Yongchao Han, Liangyao Xiong, Ying Xu, Tian Tian, Tao Wang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Closer Look at Histamine inInternational journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Science advances · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. L-Carnitine in Drosophila: A Review.Antioxidants (Basel, Switzerland) · 2020
    Review
  12. International journal of molecular sciences · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yongchao HanGraduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.ORCID 0000-0003-1965-0161
Liangyao XiongNational Institute of Biological Sciences, Beijing, China.ORCID 0000-0002-5205-8648
Ying XuNational Institute of Biological Sciences, Beijing, China.
Tian TianNational Institute of Biological Sciences, Beijing, China.
Tao WangGraduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.ORCID 0000-0002-2395-3483
Chinese Academy of Medical Sciences & Peking Union Medical College · CNBeijing Normal University · CNNational Institute of Biological Sciences, Beijing · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recycling of neurotransmitters is essential for sustained synaptic transmission. In Drosophila, histamine recycling is required for visual synaptic transmission. Synaptic histamine is rapidly taken up by laminar glia, and is converted to carcinine. After delivered back to photoreceptors, carcinine is hydrolyzed to release histamine and β-alanine. This histamine is repackaged into synaptic vesicles, but it is unclear how the β-alanine is returned to the laminar glial cells. Here, we identified a new β-alanine transporter, which we named BalaT (

Indexed as

Synaptic TransmissionAnimalsbeta-AlanineDrosophilaGene Knockout TechniquesHistamineMembrane Transport ProteinsNeurogliaRetinal Pigment Epitheliumbeta-AlanineHistamineMembrane Transport ProteinsD. melanogasterhistamine recyclingneuroscienceneurotransmitter transporterretinal pigment cell

Identifiers

PMID28806173
PMCPMC5555718
OpenAlexW2748526383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.