Evidence map›Paper›PMID 28805291›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2018

Harms of unsuccessful donation after circulatory death: An exploratory study.

Lauren J Taylor, Anne Buffington, Joseph R Scalea, Norman Fost, Kenneth D Croes, Joshua D Mezrich, Margaret L Schwarze

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnostic test accuracy for cessation of circulation during death determination: a systematic review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Pooled it
  2. Review
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  4. Review
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  8. Healthcare Worker Attitudes to Living Donation Prior to Planned Withdrawal of Care.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article
  9. Article
  10. Article
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  12. Article
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  15. Donation after circulatory death and lung transplantation.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren J TaylorDepartment of Surgery, University of Wisconsin, Madison, WI, USA.ORCID 0000-0002-7719-9025
Anne BuffingtonDepartment of Surgery, University of Wisconsin, Madison, WI, USA.
Joseph R ScaleaDepartment of Surgery, University of Maryland, Baltimore, MD, USA.
Norman FostDepartment of Pediatrics, University of Wisconsin, Madison, WI, USA.
Kenneth D CroesUniversity of Wisconsin Survey Center, Madison, WI, USA.
Joshua D MezrichDepartment of Surgery, University of Wisconsin, Madison, WI, USA.
Margaret L SchwarzeDepartment of Surgery, University of Wisconsin, Madison, WI, USA.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
UW Surgical Oncology Research Training Program (UW-SORT)T32CA090217 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Muhammed Murtaza, Heather B Neuman · 2001 to 2026
$8.3M
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NCI NIH HHS T32 CA090217
6 · The paper itself

Abstract

While donation after circulatory death (DCD) has expanded options for organ donation, many who wish to donate are still unable to do so. We conducted face-to-face interviews with family members (N = 15) who had direct experience with unsuccessful DCD and 5 focus groups with professionals involved in the donation process. We used qualitative content analysis to characterize the harms of nondonation as perceived by participants. Participants reported a broad spectrum of harms affecting organ recipients, donors, and donor families. Harms included waste of precious life-giving organs and hospital resources, inability to honor the donor's memory and character, and impaired ability for families to make sense of tragedy and cope with loss. Donor families empathized with the initial hope and ultimate despair of potential recipients who must continue their wait on the transplant list. Focus group members reinforced these findings and highlighted the struggle of families to navigate the uncertainty regarding the timing of death during the donation process. While families reported significant harm, many appreciated the donation attempt. These findings highlight the importance of organ donation to donor families and the difficult experiences associated with current processes that could inform development of alternative donation strategies.

Indexed as

DeathDecision MakingAdaptation, PsychologicalAdolescentAdultAgedAged, 80 and overCardiovascular SystemFamilyFamily ConflictFemaleFollow-Up StudiesHumansMaleMiddle AgedOrgan Transplantationdonors and donationdonors and donation: donation after circulatory death (DCD)ethics and public policyhealth services and outcomes researchorgan allocationorgan procurementorgan procurement and allocationorgan transplantation in generalqualitative research

Identifiers

PMID28805291
PMCPMC5790593

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.