Evidence map›Paper›PMID 28804725›Full record

ArticleJournal of diabetes research2017

Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes.

John E Bylander, Faihaa Ahmed, Sabena M Conley, Jean-Marie Mwiza, Elimelda Moige Ongeri

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Proteomic Study of Low-Birth-Weight Nephropathy in Rats.International journal of molecular sciences · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Matrix Metalloproteinases in Diabetic Kidney Disease.Journal of clinical medicine · 2020
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

John E BylanderDepartment of Environmental Sciences, Pennsylvania State University, Harrisburg, Middletown, PA 17057, USA.
Faihaa AhmedDepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USA.
Sabena M ConleyDepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USA.
Jean-Marie MwizaDepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USA.
Elimelda Moige OngeriDepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0002-2963-4379
North Carolina Agricultural and Technical State University · USPennsylvania State University · US

Funding

MBRS Research Initiative for Scientific Enhancement at NCATSUR25GM076162 · NIGMS · NORTH CAROLINA AGRI & TECH ST UNIV · PI MARTIN, PATRICK M · 2007 to 2017
$6.3M
MEPRINS-METALLOPROTEINSASES OF THE KIDNEY AND INTESTINER01DK019691 · NIDDK · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BOND, JUDITH S · 1986 to 2010
$3.1M
Role of Meprins in Ischemia Reperfusion induced renal injurySC3GM102049 · NIGMS · NORTH CAROLINA AGRI & TECH ST UNIV · PI ONGERI, ELIMELDA MOIGE · 2012 to 2015
$421k
MEPRINS - METALLOPROTEINASES OF THE KIDNEY AND INTESTINER56DK019691 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BOND, JUDITH S · 2005 to 2005
$73k
NIDDK NIH HHS R01 DK019691NIDDK NIH HHS R56 DK019691NIGMS NIH HHS R25 GM076162NIGMS NIH HHS SC3 GM102049
6 · The paper itself

Abstract

Meprins are membrane-bound and secreted metalloproteinases consisting of

Indexed as

AnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Diabetic NephropathiesKidney Failure, ChronicKidney Function TestsMaleMetalloendopeptidasesMiceMice, Inbred C57BLMice, KnockoutMortalitySeverity of Illness IndexStreptozocinmeprin AMetalloendopeptidasesStreptozocin

Identifiers

PMID28804725
PMCPMC5540529
OpenAlexW4236410000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.