Evidence map›Paper›PMID 28804650›Full record

ArticleAutism research and treatment2017

The 2D : 4D Digit Ratio as a Biomarker for Autism Spectrum Disorder.

M Mackus, D de Kruijff, L S Otten, A D Kraneveld, J Garssen, J C Verster

Abstract read
In one paragraph

Article in Autism research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Assessment of Immune Fitness.Journal of clinical medicine · 2022
    Review
  5. Article
  6. 2D:4D Ratio and Autism Spectrum Disorder in Brunei Darussalam.Journal of autism and developmental disorders · 2021
    Article
  7. Article
  8. Article
  9. Investigating Potential Biomarkers in Autism Spectrum Disorder.Frontiers in integrative neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M MackusDivision of Pharmacology, Utrecht University, Utrecht, Netherlands.
D de KruijffDivision of Pharmacology, Utrecht University, Utrecht, Netherlands.
L S OttenDivision of Pharmacology, Utrecht University, Utrecht, Netherlands.
A D KraneveldDivision of Pharmacology, Utrecht University, Utrecht, Netherlands.
J GarssenDivision of Pharmacology, Utrecht University, Utrecht, Netherlands.
J C VersterDivision of Pharmacology, Utrecht University, Utrecht, Netherlands.ORCID 0000-0002-6455-2096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been suggested that the second (2D, index finger) to fourth (4D, ring finger) digit ratio, 2D : 4D, may be a biomarker for the risk of developing autism. The aim of the current study was to determine the usefulness of the 2D : 4D digit ratio as biomarker for autistic traits.

Identifiers

PMID28804650
PMCPMC5540470

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.