Evidence map›Paper›PMID 28804614›Full record

ArticleIranian journal of basic medical sciences2017

Protective effect of bioactive compounds from

Yald Shokoohinia, Shekoufeh Khajouei, Farahnaz Ahmadi, Nastaran Ghiasvand, Leila Hosseinzadeh

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Comprehensive Phytochemical Characterization ofInternational journal of molecular sciences · 2026
    Article
  2. Phytochemical Analysis and Bioevaluation ofAntioxidants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. GenusPlants (Basel, Switzerland) · 2024
    Review
  5. Molecules (Basel, Switzerland) · 2023
    Article
  6. Oxypeucedanin and isoimperatorin extracted fromResearch in pharmaceutical sciences · 2022
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yald ShokoohiniaPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Shekoufeh KhajoueiPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Farahnaz AhmadiPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Nastaran GhiasvandStudent Research Committee, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Leila HosseinzadehPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Kermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe present study aims to evaluate the protective effect of the compounds isolated from MATERIALS AND

methodsSix compounds were isolated as quercetrin-3-

resultsTreatment of cells with QUE and OST before exposure to the CIS increased cell viability, i.e., these compounds protected the cells against CIS -induced cytotoxicity. In addition, pre-treatment with QUE and OST decreased CIS-induced apoptosis through up-regulation of Bcl-2, inhibition of caspase-3 activity, and mitochondrial membrane potential (MMP) increase. OST decreased ROS generation induced by CIS, as well.

conclusionOur

Indexed as

ApoptosisCisplatinEchinophora cinereaNeuroprotectionOstholeQuercetin

Identifiers

PMID28804614
PMCPMC5425927
OpenAlexW2613865185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.