Evidence map›Paper›PMID 28804539›Full record

ArticleAmerican journal of translational research2017

miR-371, miR-138, miR-544, miR-145, and miR-214 could modulate Th1/Th2 balance in asthma through the combinatorial regulation of Runx3.

Yu-Ying Qiu, Ying-Wei Zhang, Xiu-Fen Qian, Tao Bian

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Association between osteopontin expression and asthma: a meta-analysis.The Journal of international medical research · 2019
    Pooled it
  2. Distinct miRNA expression patterns in circulating eosinophil subtypes and their subtype-derived exosomes in allergic asthma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. The Role of miR-138 in Cardiovascular Diseases.BioMed research international · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Circular RNAs: emerging players in asthma and COPD.Frontiers in cell and developmental biology · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yu-Ying QiuDepartment of Respiratory Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNo. 321 Zhongshan Road, Nanjing 210008, Jiangsu, China.
Ying-Wei ZhangDepartment of Respiratory Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNo. 321 Zhongshan Road, Nanjing 210008, Jiangsu, China.
Xiu-Fen QianDepartment of Respiratory Medicine, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityNo. 299 Qingyang Road, Wuxi 214023, Jiangsu, China.
Tao BianDepartment of Respiratory Medicine, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityNo. 299 Qingyang Road, Wuxi 214023, Jiangsu, China.
Nanjing Drum Tower Hospital · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is tightly related to the imbalance of Th1/Th2 cells, and Runx3 plays a pivotal role in the differentiation of T helper cells. The present study aimed to investigate dysregulated microRNAs that may target Runx3 in CD4

Indexed as

AsthmamicroRNAregulatory T cellsRunx3

Identifiers

PMID28804539
PMCPMC5553871
OpenAlexW2959313308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.