ReviewAmerican journal of translational research2017
An integrated approach to coronary heart disease diagnosis and clinical management.
Review in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Flavonoid-Rich Extracts from Mentha Piperita and their Novel Role in ALT Modulation in a Cardiovascular Disease Rat Model.Cell biochemistry and biophysics · 2026Article
- Usefulness of the AHEAD score for prediction of all-cause death in patients with acute and chronic coronary syndromes.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Intakes of Dairy and Soy Products and 10-Year Coronary Heart Disease Risk in Korean Adults.Nutrients · 2024Article
- UltraAIGenomics: Artificial Intelligence-Based Cardiovascular Disease Risk Assessment by Fusion of Ultrasound-Based Radiomics and Genomics Features for Preventive, Personalized and Precision Medicine: A Narrative Review.Reviews in cardiovascular medicine · 2024Review
- Gensini Score's Severity and Its Relationship with Risk Factors for Coronary Artery Disease Among Patients Who Underwent Angiography in Somalia's Largest PCI Centre.International journal of general medicine · 2024Article
- Stratification of Patients with Coronary Artery Disease by Circulating Cytokines Profile: A Pilot Study.Journal of clinical medicine · 2023Article
- Editorial for Special Issue "Advance in Diagnostic and Management of Ischemic Heart Disease".Diagnostics (Basel, Switzerland) · 2023Article
- White blood cells and coronary heart disease: A mendelian randomization study.Frontiers in genetics · 2023Article
- Article
- Weighted Gene Coexpression Network Analysis Identifies Crucial Genes Involved in Coronary Atherosclerotic Heart Disease.Disease markers · 2022Article
- Recent Trends in Artificial Intelligence-Assisted Coronary Atherosclerotic Plaque Characterization.International journal of environmental research and public health · 2021Review
- Lipid biomarkers in statin users with coronary artery disease annotated by coronary computed tomography angiography.Scientific reports · 2021Article
- miR-30c-5p acts as a therapeutic target for ameliorating myocardial ischemia-reperfusion injury.American journal of translational research · 2021Article
- Molecular networks in Network Medicine: Development and applications.Wiley interdisciplinary reviews. Systems biology and medicine · 2020Review
- Network Medicine: A Clinical Approach for Precision Medicine and Personalized Therapy in Coronary Heart Disease.Journal of atherosclerosis and thrombosis · 2020Review
- Statins for the Primary Prevention of Coronary Heart Disease.BioMed research international · 2019Article
- Article
- A case of coronary arterio-venous fistula: the role of cardiac computed tomography.Journal of thoracic disease · 2018Article
- Protective effect of N-acetylcysteine activated carbon release microcapsule on myocardial ischemia-reperfusion injury in rats.Experimental and therapeutic medicine · 2018Article
- Image Quality and Dose Reduction by Dual Source Computed Tomography Coronary Angiography: Protocol Comparison.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The major issue in coronary heart disease (CHD) diagnosis and management is that symptoms onset in an advanced state of disease. Despite the availability of several clinical risk scores, the prediction of cardiovascular events is lacking, and many patients at risk are not well stratified according to the canonical risk factors alone. Therefore, adequate risk assessment remains the most challenging issue. Recently, the integration of imaging data with biochemical markers in a radiogenomic framework has been proposed in many fields of medicine as well as in cardiology. Multimodal imaging and advanced processing techniques can provide both direct (e.g., remodeling index, calcium score, total plaque volume, plaque burden) and indirect (e.g., myocardial perfusion index, coronary flow reserve) imaging features of CHD. Furthermore, the identification of novel non-invasive biochemical markers, mainly focused on plasma and/or serum samples, has increased the specificity of findings, reflecting several pathophysiological pathways of atherosclerosis, the principal actor in CHD. In this context, a multifaced approach, derived from the strengths of all these modalities, appears promising for finer risk stratification and treatment strategies, facilitating the decision-making and clinical management of patients. This review underlines the role of different imaging modalities in the quantification of coronary atherosclerosis and describes novel blood-based markers that could improve diagnosis and have a better predictive value in CHD.
Indexed as
Identifiers
28804537PMC5553869W2803947579What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.