Evidence map›Paper›PMID 28804532›Full record

ArticleOxidative medicine and cellular longevity2017

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project.

Daniela Weber, Wolfgang Stuetz, Olivier Toussaint, Florence Debacq-Chainiaux, Martijn E T Dollé, Eugène Jansen, Efstathios S Gonos, Claudio Franceschi, Ewa Sikora, Antti Hervonen and 5 more

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04763525 nacompletednot on this mapstarted 2018, after this paper: background citation

Stress and Biomarkers of Aging: a Novel Stress Management Program With the Cognitive Restructuring Method "Pythagorean Self-Awareness Intervention" in Healthy Individuals and in Subjects With Type 2 Diabetes Mellitus.

TypeinterventionalSponsorNational and Kapodistrian University of AthensRan2018 to 2019Enrolled48ConditionsType 2 Diabetes Mellitus, Telomere ShorteningArmsPythagorean Self-Awareness Intervention(PSAI)
NCT05202652 nacompletednot on this mapstarted 2019, after this paper: background citation

A Randomized, Placebo-controlled Prospective Trial for the Evaluation of Anti-oxidant, Anti-aging and Wellbeing Effects of a Novel Nutraceutical Formulation (HealthSpan)

TypeinterventionalSponsorNational Hellenic Research FoundationRan2019 to 2021Enrolled122ConditionsAging, Well Aging, Oxidative StressArmsHealthSpan, Placebo
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Biomarkers of Oxidative and Mitochondrial Stress Are Associated With Accelerated Pace of Aging at Midlife in a Birth Cohort.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 7 countries.

Daniela WeberDepartment of Molecular Toxicology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.ORCID 0000-0002-2054-6233
Wolfgang StuetzInstitute of Biological Chemistry and Nutrition, University of Hohenheim, 70599 Stuttgart, Germany.
Olivier ToussaintURBC-NARILIS, University of Namur, 5000 Namur, Belgium.
Florence Debacq-ChainiauxURBC-NARILIS, University of Namur, 5000 Namur, Belgium.
Martijn E T DolléNational Institute of Public Health and the Environment (RIVM), 3720 BA Bilthoven, Netherlands.
Eugène JansenNational Institute of Public Health and the Environment (RIVM), 3720 BA Bilthoven, Netherlands.ORCID 0000-0002-3151-5897
Efstathios S GonosInstitute of Biological Research and Biotechnology, National Hellenic Research Foundation (NHRF), 11635 Athens, Greece.
Claudio FranceschiDepartment of Experimental Pathology, University of Bologna, 40126 Bologna, Italy.
Ewa SikoraNencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Antti HervonenSchool of Medicine, University of Tampere, 33014 Tampere, Finland.
Nicolle BreusingInstitute of Biological Chemistry and Nutrition, University of Hohenheim, 70599 Stuttgart, Germany.
Thilo SindlingerMolecular Toxicology, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
María Moreno-VillanuevaMolecular Toxicology, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Alexander BürkleMolecular Toxicology, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Tilman GruneDepartment of Molecular Toxicology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
University of Konstanz · DENational Institute for Public Health and the Environment · NLUniversity of Hohenheim · DEUniversity of Namur · BEGerman Centre for Cardiovascular Research · DEGerman Institute of Human Nutrition · DEInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLNational Hellenic Research Foundation · GRTampere University · FIUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and antioxidants play a role in age-related diseases and in the aging process. We here present data on protein carbonyls, 3-nitrotyrosine, malondialdehyde, and cellular and plasma antioxidants (glutathione, cysteine, ascorbic acid, uric acid,

Indexed as

Adultalpha-TocopherolAntioxidantsAscorbic AcidBiomarkersCarotenoidsFemaleGlutathioneHumansLipid PeroxidationLycopeneMaleMalondialdehydeMiddle AgedOxidation-ReductionOxidative Stress3-nitrotyrosinealpha-TocopherolAntioxidantsAscorbic AcidBiomarkersCarotenoidsGlutathioneLycopeneMalondialdehydeTyrosineUric Acid

Identifiers

PMID28804532
PMCPMC5539926
OpenAlexW2736518260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.