Evidence map›Paper›PMID 28804482›Full record

ArticleFrontiers in immunology2017

Risk Factors for Intensive Care Unit Admission in Patients with Autoimmune Encephalitis.

Gayane Harutyunyan, Larissa Hauer, Martin W Dünser, Tobias Moser, Slaven Pikija, Markus Leitinger, Helmut F Novak, Wolfgang Aichhorn, Eugen Trinka, Johann Sellner

Abstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Autoimmune Encephalitis in Acute Care-Pathology, Diagnosis, and Management.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
  4. Article
  5. Autoimmune neurology-a rapidly evolving field.Wiener medizinische Wochenschrift (1946) · 2024
    Article
  6. Outcome and Sequelae of Autoimmune Encephalitis.Journal of clinical neurology (Seoul, Korea) · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Clinical efficacy of plasma exchange in patients with autoimmune encephalitis.Annals of clinical and translational neurology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gayane HarutyunyanDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Larissa HauerDepartment of Psychiatry and Psychotherapy, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Martin W DünserDepartment of Critical Care, University College of London Hospital, London, United Kingdom.
Tobias MoserDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Slaven PikijaDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Markus LeitingerDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Helmut F NovakDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Wolfgang AichhornDepartment of Psychiatry and Psychotherapy, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Eugen TrinkaDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.
Johann SellnerDepartment of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevention and early recognition of critical illness in patients with autoimmune encephalitis (AE) is essential to achieve better outcome. AIM OF THE STUDY: To evaluate risk factors for intensive care unit (ICU) admission and its prognostic impact in patients with AE. PATIENTS AND

methodsA reclassification of patients hospitalized between 2011 and 2016 revealed 17 "definite" and 15 "probable" AE cases. Thirteen patients (41%) developed critical illness and required ICU admission. The underlying conditions were intractable seizures or status epilepticus (54%), altered mental state (39%), and respiratory failure (8%).

resultsICU admission was associated with longer time from first symptoms to hospitalization (

conclusionWe confirmed the need for ICU care in a subgroup of patients and the prevailing objective is improved seizure control, and definite diagnosis of AE and anemia were identified as risk factors for development of critical illness. However, prognosis was not affected by ICU admission.

Indexed as

autoimmune encephalitiscritical carehumoral immunityneurodegenerationprognosisseizures

Identifiers

PMID28804482
PMCPMC5532517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.