ArticleFrontiers in neurology2017
Midterm Blood Pressure Variability Is Associated with Poststroke Cognitive Impairment: A Prospective Cohort Study.
Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Potential Biomarkers of Post-stroke Cognitive Impairment in Chinese Population: a Systematic Review and Meta-Analysis.Molecular neurobiology · 2025Pooled it
- Association between Blood Pressure and Post-Stroke Cognitive Impairment: A Meta-Analysis.Reviews in cardiovascular medicine · 2024Pooled it
- Blood pressure variability and cognitive dysfunction: A systematic review and meta-analysis of longitudinal cohort studies.Journal of clinical hypertension (Greenwich, Conn.) · 2021Pooled it
- Blood pressure parameters and cognitive decline and dementia after stroke or transient ischemic attack: results from the PROGRESS trial.American journal of hypertension · 2026Trial
- Blood pressure variability and the risk of post-stroke cognitive impairment following atrial fibrillation related acute ischemic stroke.Clinical hypertension · 2026Article
- Article
- Characterization and individual-level prediction of cognitive state in the first year after 'mild' stroke.PloS one · 2024Article
- Higher soluble TREM-1 levels are associated with cognitive impairment after acute ischemic stroke.Frontiers in aging neuroscience · 2024Article
- A nomogram incorporating red blood cell indices to predict post-stroke cognitive impairment in the intracerebral hemorrhage population.Frontiers in aging neuroscience · 2022Article
- The Effects of Enriched Rehabilitation on Cognitive Function and Serum Glutamate Levels Post-stroke.Frontiers in neurology · 2022Article
- Association between Blood Pressure, Blood Pressure Variability, and Post-Stroke Cognitive Impairment.Biomedicines · 2021Review
- Elevated Serum Amyloid A Is Associated With Cognitive Impairment in Ischemic Stroke Patients.Frontiers in neurology · 2021Article
- Low Hemoglobin Levels at Admission Are Independently Associated with Cognitive Impairment after Ischemic Stroke: a Multicenter, Population-Based Study.Translational stroke research · 2020Article
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate the relationship between blood pressure variability (BPV) and poststroke cognitive impairment (PSCI).
methodsSeven-hundred ninety-six patients with acute ischemic stroke were included in this study. Midterm BPV was evaluated by calculating the SD and coefficient of variation (CV, 100 × SD/mean) of systolic blood pressure (SBP) and diastolic blood pressure during the 7 days after stroke onset. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) at admission and at all follow-up visits. Patients with MoCA scores <26 were considered to have PSCI.
resultsThe incidence of PSCI reached its peak (72%) 3 months after stroke onset and decreased to 30.3% at 12 months poststroke. After adjusting for covariables, the increase in the prevalence of PSCI at 3 months was independently associated with increases in the CV of blood pressure during the 7 days after stroke [odds ratios and 95% CI for patients in the second to fifth quintiles of SBP CV were 2.28 (1.18, 4.39), 2.33 (1.18, 4.62), 2.69 (1.31, 5.53), and 4.76 (1.95, 11.67), respectively]. Sub-analysis of the MoCA scores revealed that the patients had impairments in visuoperceptual abilities and executive functions, as well as in naming and delayed recall (
conclusionMidterm BPV during the early phase of acute ischemic stroke is independently associated with PSCI, especially in the visuoperceptual, executive, and delayed recall domains. CLINICAL
trial registrationhttp://www.chictr.org.cn, identifier ChiCTR-TRC-14004804.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.