Evidence map›Paper›PMID 28804453›Full record

ArticleFrontiers in human neuroscience2017

Delta Power Is Higher and More Symmetrical in Ischemic Stroke Patients with Cortical Involvement.

Chiara Fanciullacci, Federica Bertolucci, Giuseppe Lamola, Alessandro Panarese, Fiorenzo Artoni, Silvestro Micera, Bruno Rossi, Carmelo Chisari

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04688970 (Personalized Neurorehabilitative Precision Medicine - From Data to Therapies), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04688970 unknown statusnot on this mapstarted 2020, after this paper: background citation

Personalized Neurorehabilitative Precision Medicine - From Data to Therapies

TypeobservationalSponsorUniversity Hospital TuebingenRan2020 to 2022Enrolled500ConditionsStroke, Acute, Outcome, Improvement, Rehabilitation, Upper Extremity ParesisArmsno intervention
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Association between lesion location and sensorimotor rhythms in stroke - a systematic review with narrative synthesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Pooled it
  2. Quantitative measures of the resting EEG in stroke: a systematic review on clinical correlation and prognostic value.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chiara FanciullacciNeurorehabilitation Unit, University Hospital of PisaUniversity of Pisa, Pisa, Italy.
Federica BertolucciNeurorehabilitation Unit, University Hospital of PisaUniversity of Pisa, Pisa, Italy.
Giuseppe LamolaNeurorehabilitation Unit, University Hospital of PisaUniversity of Pisa, Pisa, Italy.
Alessandro PanareseThe BioRobotic Institute, Scuola Superiore Sant'AnnaPisa, Italy.
Fiorenzo ArtoniThe BioRobotic Institute, Scuola Superiore Sant'AnnaPisa, Italy.
Silvestro MiceraThe BioRobotic Institute, Scuola Superiore Sant'AnnaPisa, Italy.
Bruno RossiNeurorehabilitation Unit, University Hospital of PisaUniversity of Pisa, Pisa, Italy.
Carmelo ChisariNeurorehabilitation Unit, University Hospital of PisaUniversity of Pisa, Pisa, Italy.
Scuola Superiore Sant'Anna · ITUniversity of Pisa · ITAzienda Ospedaliera Universitaria Pisana · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A brain injury resulting from unilateral stroke critically alters brain functionality and the complex balance within the cortical activity. Such modifications may critically depend on lesion location and cortical involvement. Indeed, recent findings pointed out the necessity of applying a stratification based on lesion location when investigating inter-hemispheric balance in stroke. Here, we tested whether cortical involvement could imply differences in band-specific activity and brain symmetry in post stroke patients with cortico-subcortical and subcortical strokes. We explored brain activity related to lesion location through EEG power analysis and quantitative Electroencephalography (qEEG) measures. Thirty stroke patients in the subacute phase and 10 neurologically intact age-matched right-handed subjects were enrolled. Stroke patients were equally subdivided in two groups based on lesion location: cortico-subcortical (CS, mean age ± SD: 72.21 ± 10.97 years; time since stroke ± SD: 31.14 ± 11.73 days) and subcortical (S, mean age ± SD: 68.92 ± 10.001 years; time since stroke ± SD: 26.93 ± 13.08 days) group. We assessed patients' neurological status by means of National Institutes of Health Stroke Scale (NIHSS). High density EEG at rest was recorded and power spectral analysis in Delta (1-4 Hz) and Alpha (8-14 Hz) bands was performed. qEEG metrics as pairwise derived Brain Symmetry Index (pdBSI) and Delta/Alpha Ratio (DAR) were computed and correlated with NIHSS score. S showed a lower Delta power in the Unaffected Hemisphere (UH) compared to Affected Hemisphere (AH;

Indexed as

brain asymmetrycerebrovascular diseaseclinical neurophysiologyneuronal plasticityquantitative electroencephalographystroke

Identifiers

PMID28804453
PMCPMC5532374
OpenAlexW2741093459

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.