Evidence map›Paper›PMID 28804447›Full record

ArticleFrontiers in molecular neuroscience2017

Activity-Dependent Arc Expression and Homeostatic Synaptic Plasticity Are Altered in Neurons from a Mouse Model of Angelman Syndrome.

Elissa D Pastuzyn, Jason D Shepherd

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. "Arc - A viral vector of memory and synaptic plasticity".Current opinion in neurobiology · 2025
    Review
  7. Article
  8. Ubiquitin system mutations in neurological diseases.Trends in biochemical sciences · 2024
    Review
  9. Diverging from the Norm: Reevaluating What Miniature Excitatory Postsynaptic Currents Tell Us about Homeostatic Synaptic Plasticity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  10. Article
  11. Article
  12. Arc ubiquitination regulates endoplasmic reticulum-mediated CaFrontiers in cellular neuroscience · 2023
    Article
  13. Stem cell models of Angelman syndrome.Frontiers in cell and developmental biology · 2023
    Review
  14. 'Arc'-hitecture of normal cognitive aging.Ageing research reviews · 2022
    Review
  15. Article
  16. Article
  17. Leftovers of viruses in human physiology.Brain structure & function · 2021
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elissa D PastuzynDepartment of Neurobiology and Anatomy, University of UtahSalt Lake City, UT, United States.
Jason D ShepherdDepartment of Neurobiology and Anatomy, University of UtahSalt Lake City, UT, United States.
University of Utah · US

Funding

DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007491 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI James Alan Gagnon, Kristen M Kwan · 1995 to 2026
$8.0M
Investigating the mechanisms of Arc‐dependent synaptic plasticityR01MH112766 · NIMH · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jason D Shepherd · 2017 to 2026
$4.2M
Role of Arc in synaptic/experience-dependent plasticity in mouse visual cortexR00NS076364 · NINDS · UNIVERSITY OF UTAH · PI SHEPHERD, JASON D · 2013 to 2015
$717k
NICHD NIH HHS T32 HD007491NIMH NIH HHS R01 MH112766NINDS NIH HHS R00 NS076364
6 · The paper itself

Abstract

Angelman syndrome (AS) is a neurodevelopmental disorder that results from deletions or mutations in chromosome 15, which usually includes the

Indexed as

Angelman syndromeArchippocampushomeostatic scalingsynaptic plasticity

Identifiers

PMID28804447
PMCPMC5532393
OpenAlexW2741074105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.