ArticleHeart and vessels2018
Specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients.
Article in Heart and vessels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- The association between the oral microbiome and hypertension: a systematic review.Journal of oral microbiology · 2025Article
- The Oral-Gut-Brain Axis: The Influence of Microbes as a Link of Periodontitis With Ischemic Stroke.CNS neuroscience & therapeutics · 2024Review
- [The characteristics of pharyngea microbiological in children with obstructive sleep apnea].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024Article
- Article
- Salivary microbial shifting in hypertensive patients with chronic periodontitis after scaling and root surface debridement.Molecular biology reports · 2024Observational
- [Latest Research Findings on the Mechanism of Periodontal Pathogens in Cardiovascular Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Review
- Periodontal and systemic health of morbidly obese patients eligible for bariatric surgery: a cross-sectional study.BMC oral health · 2022Article
- The Impact of Hypertension and Use of Calcium Channel Blockers on Tuberculosis Treatment Outcomes.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Dysbiosis of the Salivary Microbiome is Associated with Hypertension and Correlated with Metabolic Syndrome Biomarkers.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- A review of the association between oral bacterial flora and obstructive sleep apnea-hypopnea syndrome comorbid with cardiovascular disease.Sleep & breathing = Schlaf & Atmung · 2020Review
- How Periodontal Disease and Presence of Nitric Oxide Reducing Oral Bacteria Can Affect Blood Pressure.International journal of molecular sciences · 2020Review
- Analysis of oral microbiota in patients with obstructive sleep apnea-associated hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Accelerated inflammation in peripheral artery disease patients with periodontitis.Journal of periodontal & implant science · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Hypertension (HT) is a systemic disorder that results in the decline of quality of life and death. While patients with periodontitis are at a high risk of HT, little causal information has been provided to date. To clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without HT was evaluated. The subjects were patients with (n = 412) or without (n = 199) HT who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed. Three periodontopathic bacteria existence and antibody titers were evaluated. We found that specific periodontopathic bacteria, Aggregatibacter actinomycetemcomitans and Prevotella intermedia, were highly detected in male subjects with HT compared to non-HT subjects, while they were comparable in the female patients. Mean probing pocket depth of elderly male patients with HT was higher compared to non-HT patients. The rates of obesity, dyslipidemia, and diabetes showed partial statistical difference between the two groups. Specific periodontopathic bacterial infection may affect HT in male cardiovascular patients.
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Registered trials
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