ArticleClinical rheumatology2018
Dual-energy computed tomography has limited diagnostic sensitivity for short-term gout.
Article in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05698680 (Pragmatic, Randomized, Multicenter, Double-blind, Controlled, Clinical Trial of Prednisolone Versus Colchicine for Acute Gout in Primary Care), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pragmatic, Randomized, Multicenter, Double-blind, Controlled, Clinical Trial of Prednisolone Versus Colchicine for Acute Gout in Primary Care
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- 2023 EULAR recommendations on imaging in diagnosis and management of crystal-induced arthropathies in clinical practice.Annals of the rheumatic diseases · 2024Guideline
- Comparison of efficacy and safety of urate-lowering therapies for hyperuricemic patients with gout: a meta-analysis of randomized, controlled trials.Clinical rheumatology · 2021Pooled it
- Clinical utility of Dual Energy Computed Tomography in gout: current concepts and applications.Acta bio-medica : Atenei Parmensis · 2020Pooled it
- DECTGoutSys: Reducing False Positive Gout Diagnoses via a Machine Vision Pipeline for Crystal Tophi Identification+Classification in Dual-Energy Computed Tomography (DECT).Journal of imaging informatics in medicine · 2026Article
- Combination of dual-energy CT findings and clinical features predicts risk of frequent flares of gout.European radiology · 2026Article
- Status, challenges, and prospects of artificial intelligence application in gout diagnosis and treatment, drug research and development, and disease monitoring.Frontiers in medicine · 2026Review
- The comprehensive role of dual-energy CT in gout as an advanced diagnostic innovation.Skeletal radiology · 2025Review
- Deep learning reconstruction enhances tophus detection in a dual-energy CT phantom study.Scientific reports · 2025Article
- Imaging of gout: an atlas.Rheumatology advances in practice · 2025Review
- Imaging methods in monitoring gout - a pictorial essay.Journal of ultrasonography · 2024Article
- Ultrasound Features in Gout: An Overview.Medical sciences (Basel, Switzerland) · 2024Review
- Updates on the Applications of Spectral Computed Tomography for Musculoskeletal Imaging.Diagnostics (Basel, Switzerland) · 2024Review
- The Clinical Utility of Dual-Energy Computed Tomography in the Diagnosis of Gout-A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- The role of dual energy computed tomography in the differentiation of acute gout flares and acute calcium pyrophosphate crystal arthritis.Clinical rheumatology · 2022Article
- Reliability of knee joint sonography in the evaluation of gouty arthritis.Journal of ultrasonography · 2021Article
- Limitations of dual-energy CT in the detection of monosodium urate deposition in dense liquid tophi and calcified tophi.Skeletal radiology · 2021Article
- What Has Dual Energy CT Taught Us About Gout?Current rheumatology reports · 2021Review
- What is the diagnostic value of dual-energy computed tomography in patients with clinical diagnosis of gout?Advances in rheumatology (London, England) · 2021Article
- Gout of feet and ankles in different disease durations: diagnostic value of single-source DECT and evaluation of urate deposition with a novel semi-quantitative DECT scoring system.Advances in rheumatology (London, England) · 2021Article
- Combining non-contrast and dual-energy CT improves diagnosis of early gout.European radiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to discuss the diagnostic value of dual-energy computed tomography (DECT) in patients with gout during different disease phases. Two hundred twenty-one patients (136 with gout and 85 with other arthritic diseases) were recruited to the study. Arthrosis pain was evaluated in all patients by DECT scans. We calculated the sensitivity and specificity of DECT for the diagnosis of gout, including the first onset period, less than 24 months period, and more than 24 months period. We then investigated the related risk factors of urate crystals volume in the foot. The diagnostic sensitivity of DECT in the first onset, less than 24 months, and more than 24 months groups was 35.71, 61.54, and 92.86%, respectively. The overall sensitivity and specificity values were 80.88 and 88.24%, respectively. The multilinear regression analysis showed that longer disease duration (P = 0.001) and higher serum uric acid (SUA) (P = 0.001) were the two important predictive factors of the monosodium urate (MSU) crystal volume in the foot. DECT provides good diagnostic accuracy for detection of MSU crystal deposits in gout patients. However, DECT has limited diagnostic sensitivity for short-term gout patients, especially for the first onset patients. Longer disease duration and higher SUA were predictive factors of MSU crystal volume.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.