Evidence map›Paper›PMID 28802550›Full record

ArticleJournal of vascular and interventional radiology : JVIR2017

MR Coagulation: A Novel Minimally Invasive Approach to Aneurysm Repair.

Ouri Cohen, Ming Zhao, Erez Nevo, Jerome L Ackerman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Magnetic Resonance Mediated Radiofrequency Ablation.IEEE transactions on medical imaging · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ouri CohenAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts; Department of Radiology, Harvard Medical School, Boston, Massachusetts. Electronic address: ouri@nmr.mgh.harvard.edu.
Ming ZhaoAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts; Department of Physics and Applied Physics, University of Massachusetts Lowell, Lowell, Massachusetts.
Erez NevoRobin Medical Inc., Baltimore, Maryland.
Jerome L AckermanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts; Department of Radiology, Harvard Medical School, Boston, Massachusetts.
Harvard University · USUniversity of Massachusetts Lowell · US

Funding

ULTRAHIGH FIELD TECHNOLOGY FOR FUNCTIONAL IMAGINGP41RR014075 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 1999 to 2011
$16.4M
15T ULTRAHIGH FIELD MR MICROSCOPE FOR MOUSE IMAGING: TISSUE ENGINEERINGS10RR023009 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ACKERMAN, JEROME L · 2006 to 2006
$2.0M
Development and testing of MRI-mediated radiofrequency ablation system and probesR44CA203276 · NCI · ROBIN MEDICAL, INC. · PI ACKERMAN, JEROME L, NEVO, EREZ · 2016 to 2017
$1.5M
NCI NIH HHS R44 CA203276NCRR NIH HHS P41 RR014075NCRR NIH HHS S10 RR023009
6 · The paper itself

Abstract

purposeTo demonstrate a proof of concept of magnetic resonance (MR) coagulation, in which MR imaging scanner-induced radiofrequency (RF) heating at the end of an intracatheter long wire heats and coagulates a protein solution to effect a vascular repair by embolization. MATERIALS AND

methodsMR coagulation was simulated by finite-element modeling of electromagnetic fields and specific absorption rate (SAR) in a phantom. A glass phantom consisting of a spherical cavity joined to the side of a tube was incorporated into a flow system to simulate an aneurysm and flowing blood with velocities of 0-1.7 mL/s. A double-lumen catheter containing the wire and fiberoptic temperature sensor in 1 lumen was passed through the flow system into the aneurysm, and 9 cm

resultsThe protein coagulation temperature of 60°C was reached in the aneurysm in ∼12 seconds, yielding a coagulated mass that largely filled the aneurysm. The heating rate was controlled by adjusting pulse-sequence parameters.

conclusionsMR coagulation has the potential to embolize vascular defects by coagulating a protein solution delivered by catheter using MR imaging scanner-induced RF heating of an intracatheter wire.

Indexed as

AneurysmEgg WhiteEquipment DesignFinite Element AnalysisHyperthermia, InducedMagnetic Resonance ImagingPhantoms, ImagingProof of Concept StudyRadio Waves

Identifiers

PMID28802550
PMCPMC5657436
OpenAlexW2743584562

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.