Evidence map›Paper›PMID 28802259›Full record

ArticleRNA (New York, N.Y.)2017

Jun Cheng, Kerstin C Maier, Žiga Avsec, Petra Rus, Julien Gagneur

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Unlock the sustained therapeutic efficacy of mRNA.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Review
  4. DecodingbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Modulation of miRISC-Mediated Gene Silencing in Eukaryotes.Frontiers in molecular biosciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun ChengDepartment of Informatics, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0001-5573-9791
Kerstin C MaierDepartment of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Žiga AvsecDepartment of Informatics, Technical University of Munich, 85748 Garching, Germany.
Petra RusDepartment of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Julien GagneurDepartment of Informatics, Technical University of Munich, 85748 Garching, Germany gagneur@in.tum.de.ORCID 0000-0002-8924-8365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The stability of mRNA is one of the major determinants of gene expression. Although a wealth of sequence elements regulating mRNA stability has been described, their quantitative contributions to half-life are unknown. Here, we built a quantitative model for

Indexed as

3' Untranslated RegionsBase SequenceCodonGene Knockout TechniquesGenes, FungalHalf-LifeModels, BiologicalNonsense Mediated mRNA DecayPeptide Chain Initiation, TranslationalRegulatory Elements, TranscriptionalRNA, FungalRNA, MessengerRNA StabilitySaccharomyces cerevisiaeSchizosaccharomyces3' Untranslated RegionsCodonRNA, FungalRNA, Messengercis-regulatory elementscodon optimalitymRNA half-life

Identifiers

PMID28802259
PMCPMC5648033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.