Evidence map›Paper›PMID 28802034›Full record

ArticleCell2017

Keeping the Rhythm while Changing the Lyrics: Circadian Biology in Aging.

Fumiyuki Hatanaka, Alejandro Ocampo, Juan Carlos Izpisua Belmonte

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Unraveling links between aging, circadian rhythm and cancer: Insights from evidence-based analysis.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
    Article
  3. Article
  4. Dominant constraints on the evolution of rhythmic gene expression.Computational and structural biotechnology journal · 2023
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Fumiyuki HatanakaGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Universidad Católica San Antonio de Murcia (UCAM), Guadalupe 30107 Murcia, Spain.
Alejandro OcampoGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Juan Carlos Izpisua BelmonteGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: belmonte@salk.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging and circadian rhythms have been linked for decades, but their molecular interplay has remained obscure. Sato et al. and Solanas et al. now reveal that, while core clock components remain nearly unaltered, aging is associated with tissue-specific rewiring, which can be prevented by calorie restriction.

Indexed as

AgingCircadian RhythmCaloric Restriction

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.