ArticlePsycho-oncology2018
Mediating burden and stress over time: Caregivers of patients with primary brain tumor.
Article in Psycho-oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Carer preparedness improved by providing a supportive educational intervention for carers of patients with high-grade glioma: RCT results.Journal of neuro-oncology · 2023Trial
- The Bereavement Experience for Partners of Patients With Central Nervous System Tumors.Oncology nursing forum · 2022Trial
- Outcomes of an electronic social network intervention with neuro-oncology patient family caregivers.Journal of neuro-oncology · 2018Trial
- The CARING intervention for neuro-oncology family caregivers: Primary outcomes from an abbreviated randomized controlled trial.Neuro-oncology practice · 2026Article
- Associations of Critical Relationships With Distress and Burden in Caregivers of Patients With Brain Tumor.Psycho-oncology · 2025Article
- Predicting Caregiver Anxiety and Depression From Patient Distress in Brain Tumor Dyads: Actor-Partner Interdependence Model.Cancer medicine · 2025Observational
- The mediation role of hope and social support in the relationship between fatigue and burden in caregivers of patients with brain tumor.BMC cancer · 2025Article
- "You sure feel like you're alone, kind of flailing away out there": Family caregiver perspectives of caring for an individual with glioblastoma multiforme.Palliative & supportive care · 2025Article
- Longitudinal Psychological Distress After Malignant Brain Tumor Diagnosis: A Multilevel Analysis of Patients and Their Caregivers.Psycho-oncology · 2025Observational
- The cancer caregiving burden trajectory over time: varying experiences of perceived versus objectively measured burden.The oncologist · 2024Article
- Social determinants of health, psychological distress, and caregiver burden among informal cancer caregivers of cancer survivors during treatment.Journal of psychosocial oncology · 2024Article
- Hospice Caregivers' Perception of Family and Non-Family Social Support and Stress over Time: Associations with Reports of General Support.International journal of environmental research and public health · 2023Article
- Adaptation of families of adult patients with brain tumor: Partial least squares structural equation modeling.PloS one · 2023Article
- Article
- The Aftercare Survey: Assessment and intervention practices after brain tumor surgery in Europe.Neuro-oncology practice · 2022Article
- Easing the Journey-an Updated Review of Palliative Care for the Patient with High-Grade Glioma.Current oncology reports · 2022Review
- Social relationships and relational pain in brain tumor patients and their partners.Frontiers in pain research (Lausanne, Switzerland) · 2022Review
- Informal caregiver burden for solid tumour cancer patients: a review and future directions.Psychology & health · 2021Review
- Existential distress in patients with advanced cancer and their caregivers: study protocol of a longitudinal cohort study.BMJ open · 2021Article
- Caregiver Burden Domains and Their Relationship with Anxiety and Depression in the First Six Months of Cancer Diagnosis.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
There is a growing literature on the effects of cancer caregiving on the well-being of informal family caregivers. However, there has been little longitudinal research on caregivers of patients with the complex, rapidly-changing disease of primary malignant brain tumor.
objectiveOur objective was to model longitudinal relationships between caregiver burden, social support, and distress within caregivers of patients with primary brain tumor.
methodsCaregiver participants were recruited from a neuro-oncology clinic. Caregiver questionnaire data, including sociodemographics, social support, depression, anxiety, and caregiving burden, were collected at 4 time points (diagnosis, +4, +8, and +12 mo). Using the stress process model as a guide, we hypothesized that early burden would predict later depression and anxiety, and this would be mediated by social support.
resultsUsing data from 147 participants, we found support for the stress process model in caregivers of patients with primary brain tumor. Greater burden at diagnosis was associated with lower social support at 4 months, and lower social support was related to higher depression and anxiety at 8 months, as well as to changes in anxiety between 8 and 12 months.
conclusionWe found evidence of the stress process model in caregivers of primary brain tumor patients unfolding over the course of a year after diagnosis. Our findings emphasize the potential importance of early programs for caregivers to ensure low initial levels of burden, which may have a positive effect on social support, depression, and anxiety.
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