ReviewCurrent treatment options in gastroenterology2017
Intractable Constipation in the Elderly.
Review in Current treatment options in gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Effect of external therapies of traditional Chinese medicine on constipation in patients with CRF: A meta-analysis.PloS one · 2023Pooled it
- Influence of Flax Seeds on the Gut Microbiota of Elderly Patients with Constipation.Journal of multidisciplinary healthcare · 2022Trial
- Effects of Dietary Fiber Supplementation on Chronic Constipation in the Elderly: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Foods (Basel, Switzerland) · 2025Review
- Gastrointestinal Characteristics of Constipation from the Perspectives of Microbiome and Metabolome.Digestive diseases and sciences · 2024Article
- Effectiveness and safety of lubiprostone after switching from stimulant laxatives in elderly patients with chronic constipation.JGH open : an open access journal of gastroenterology and hepatology · 2023Article
- Article
- Impact of constipation on progression of Alzheimer's disease: A retrospective study.CNS neuroscience & therapeutics · 2022Article
- Alteration of Serum Metabolites in Women of Reproductive Age with Chronic Constipation.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Association of sleep duration with chronic constipation among adult men and women: Findings from the National Health and Nutrition Examination Survey (2005-2010).Frontiers in neurology · 2022Article
- Comparison of the Efficacy and Safety of Different Doses of Linaclotide for Patients with Chronic Constipation: A Meta-Analysis and Bayesian Analysis.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Changes in Treatment of Very Elderly Patients Six Weeks after Discharge from Geriatrics Department.Geriatrics (Basel, Switzerland) · 2020Article
- Article
- Effect of bisacodyl on rats with slow transit constipation.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementChronic constipation is a common gastrointestinal disorder disproportionately affecting the elderly. Immobility, polypharmacy, and physiologic changes contribute to its increased prevalence in this population. Unidentified and undertreated constipation leads to a significant negative impact on quality of life and an increase in healthcare spending. Careful physical examination and exploration of the clinical history can unmask primary and secondary forms of constipation, guiding diagnostic and therapeutic considerations. Non-pharmacologic treatment options include bowel training and biofeedback as well as the addition of fiber. Laxatives are safe and can be used long term; thus, they remain the mainstay of therapy. Newer agents with specific physiologic targets have proven to be effective in adults with chronic constipation, but data is lacking for safety profile in the elderly. Consideration for surgery in medically refractory cases should be entertained, while use of neuromodulation is not ready for prime time. This is a review of the currently available treatment options for chronic constipation in adults and specifically tailored towards the elderly.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.