Evidence map›Paper›PMID 28801682›Full record

ArticleScientific reports2017

Water ingestion decreases cardiac workload time-dependent in healthy adults with no effect of gender.

Cathriona Rosemary Monnard, Erik Konrad Grasser

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Dose-dependent heart rate responses to drinking water: a randomized crossover study in young, non-obese males.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cathriona Rosemary MonnardDepartment of Medicine/Physiology, University of Fribourg, Chemin du Musée 5, 1700, Fribourg, Switzerland.
Erik Konrad GrasserDepartment of Medicine/Physiology, University of Fribourg, Chemin du Musée 5, 1700, Fribourg, Switzerland. erikkonrad.grasser@unifr.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ingestion of water entails a variety of cardiovascular responses. However, the precise effect remains elusive. We aimed to determine in healthy adults the effect of water on cardiac workload and to investigate potential gender differences. We pooled data from two controlled studies where blood pressure (BP) and heart rate (HR) were continuously recorded before and after the ingestion of 355 mL of tap water. Additionally, we calculated double product by multiplying systolic BP with HR and evaluated spectral parameters referring to vagal tone. All parameters were investigated for potential differences based on gender. In response to water, HR, systolic BP, and double product decreased significantly during the first 30 min. However, these effects were attenuated for HR and double product and even abolished for systolic BP over the subsequent 30 min. Over the entire post-drink period (60 min), decreases in HR and double product (all P < 0.05) were observed. Spectral markers for vagal tone increased with the on-set of the water drink and remained elevated until the end (P < 0.005). No significant gender difference in cardiac workload parameters was observed. We provide evidence that drinking water decreases, in a time-dependent fashion, cardiac workload and that these responses appear not to be influenced by gender.

Indexed as

AdultBlood PressureCross-Over StudiesDrinking WaterFemaleHeartHeart RateHumansMaleRandomized Controlled Trials as TopicRetrospective StudiesStroke VolumeTime FactorsYoung AdultDrinking Water

Identifiers

PMID28801682
PMCPMC5554208

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.