ArticleScientific reports2017
Small secreted proteins from the necrotrophic conifer pathogen Heterobasidion annosum s.l. (HaSSPs) induce cell death in Nicotiana benthamiana.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 29 citations in OpenAlex.
- Genotype-by-genotype interactions reveal transcription patterns underlying resistance responses in Norway spruce to Heterobasidion annosum s.s.BMC plant biology · 2025Article
- Apoplastic effector candidates of a foliar forest pathogen trigger cell death in host and non-host plants.Scientific reports · 2021Article
- Identification and characterization of Cercospora beticola necrosis-inducing effector CbNip1.Molecular plant pathology · 2021Article
- Proteinaceous effector discovery and characterization in filamentous plant pathogens.Molecular plant pathology · 2020Review
- Functional analysis of RXLR effectors from the New Zealand kauri dieback pathogen Phytophthora agathidicida.Molecular plant pathology · 2020Article
- Using the CODIT model to explain secondary metabolites of xylem in defence systems of temperate trees against decay fungi.Annals of botany · 2020Review
- Genome sequencing of Rigidoporus microporus provides insights on genes important for wood decay, latex tolerance and interspecific fungal interactions.Scientific reports · 2020Article
- The Conifer Root and Stem Rot Pathogen (Microorganisms · 2019Article
- Overexpression ofInternational journal of molecular sciences · 2019Article
- Comparative secretome analysis of different smut fungi and identification of plant cell death-inducing secreted proteins from Tilletia horrida.BMC plant biology · 2019Article
- Genome description of Phlebia radiata 79 with comparative genomics analysis on lignocellulose decomposition machinery of phlebioid fungi.BMC genomics · 2019Article
- Dual RNA-seq analysis provides new insights into interactions between Norway spruce and necrotrophic pathogen Heterobasidion annosum s.l.BMC plant biology · 2019Article
- Characterization of Heterobasidion occidentale transcriptomes reveals candidate genes and DNA polymorphisms for virulence variations.Microbial biotechnology · 2018Article
- A role for small secreted proteins (SSPs) in a saprophytic fungal lifestyle: Ligninolytic enzyme regulation in Pleurotus ostreatus.Scientific reports · 2017Article
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2 authors at 1 institution in 1 country.
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Abstract
The basidiomycete Heterobasidion annosum sensu lato (s.l.) is considered to be one of the most destructive conifer pathogens in the temperate forests of the northern hemisphere. H. annosum is characterized by a dual fungal lifestyle. The fungus grows necrotrophically on living plant cells and saprotrophically on dead wood material. In this study, we screened the H. annosum genome for small secreted proteins (HaSSPs) that could potentially be involved in promoting necrotrophic growth during the fungal infection process. The final list included 58 HaSSPs that lacked predictable protein domains. The transient expression of HaSSP encoding genes revealed the ability of 8 HaSSPs to induce cell chlorosis and cell death in Nicotiana benthamiana. In particular, one protein (HaSSP30) could induce a rapid, strong, and consistent cell death within 2 days post-infiltration. HaSSP30 also increased the transcription of host-defence-related genes in N. benthamiana, which suggested a necrotrophic-specific immune response. This is the first line of evidence demonstrating that the H. annosum genome encodes HaSSPs with the capability to induce plant cell death in a non-host plant.
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