Evidence map›Paper›PMID 28801643›Full record

ArticleScientific reports2017

The Role of PGE

Thomas Bärnthaler, Jovana Maric, Wolfgang Platzer, Viktoria Konya, Anna Theiler, Carina Hasenöhrl, Benjamin Gottschalk, Sandra Trautmann, Yannick Schreiber, Wolfgang F Graier and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  4. Prostaglandin EFrontiers in pharmacology · 2025
    Article
  5. Pulmonary surfactant and prostaglandin EPhysiological reports · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Eosinophil-Epithelial Cell Interactions in Asthma.International archives of allergy and immunology · 2024
    Review
  10. Article
  11. Review
  12. Clinical Translation of Engineered Pulmonary Vascular Models.Advances in experimental medicine and biology · 2023
    Article
  13. A multiplex inhalation platform to modelFrontiers in pharmacology · 2023
    Article
  14. Article
  15. Antiviral Activity of a Cyclic Pro-Pro-Molecules (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Article
  18. A20 Is Increased in Fetal Lung in a Sheep LPS Model of Chorioamnionitis.Oxidative medicine and cellular longevity · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Thomas BärnthalerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Jovana MaricInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Wolfgang PlatzerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Viktoria KonyaInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Anna TheilerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Carina HasenöhrlInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Benjamin GottschalkInstitute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Sandra TrautmannPharmazentrum Frankfurt/ZAFES Institute of Clinical Pharmacology, Goethe-University Frankfurt, Frankfurt, Germany.
Yannick SchreiberFraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group TMP, Frankfurt, Germany.
Wolfgang F GraierInstitute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.ORCID 0000-0003-1871-3298
Rudolf SchichoInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Gunther MarscheInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Andrea OlschewskiLudwig Boltzmann Institute Lung Vascular Research, Graz, Austria.
Dominique ThomasPharmazentrum Frankfurt/ZAFES Institute of Clinical Pharmacology, Goethe-University Frankfurt, Frankfurt, Germany.
Rufina SchuligoiInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Akos HeinemannInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria. akos.heinemann@medunigraz.at.
Medical University of Graz · ATGoethe University Frankfurt · DEFraunhofer Institute for Molecular Biology and Applied Ecology · DELudwig Boltzmann Institute for Lung Vascular Research · AT

Funding

Austrian Science Fund FWF KLI 521Austrian Science Fund FWF P 25633Austrian Science Fund FWF P 26185
6 · The paper itself

Abstract

Disruption of the blood-air barrier, which is formed by lung microvascular endothelial and alveolar epithelial cells, is a hallmark of acute lung injury. It was shown that alveolar epithelial cells release an unidentified soluble factor that enhances the barrier function of lung microvascular endothelial cells. In this study we reveal that primarily prostaglandin (PG) E

Indexed as

Blood-Air BarrierCell CommunicationA549 CellsAlveolar Epithelial CellsAnimalsCulture Media, ConditionedCyclooxygenase 2DinoprostoneElectric ImpedanceEndothelial CellsHumansMice, Inbred BALB CReceptors, Prostaglandin E, EP4 SubtypeCulture Media, ConditionedCyclooxygenase 2DinoprostoneReceptors, Prostaglandin E, EP4 Subtype

Identifiers

PMID28801643
PMCPMC5554158
OpenAlexW2744852474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.