Evidence map›Paper›PMID 28801558›Full record

ArticleScientific reports2017

Visceral adiposity index, lipid accumulation product and intracranial atherosclerotic stenosis in middle-aged and elderly Chinese.

Rui Li, Qi Li, Min Cui, Zegang Ying, Lin Li, Tingting Zhong, Yingchao Huo, Peng Xie

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Rui LiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Qi LiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Min CuiDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Zegang YingDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Lin LiDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Tingting ZhongDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Yingchao HuoDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Peng XieDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. xiepeng@cqmu.edu.cn.
Daping Hospital · CNArmy Medical University · CNChongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CNSouth Australian Health and Medical Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the association of the newly established lipid accumulation product (LAP) and visceral adiposity index (VAI) with intracranial atherosclerotic stenosis (ICAS) in middle-aged and elderly Chinese. From June 2012 to January 2013, consecutive patients ≥40 years of age who underwent cerebral vascular imaging for various medical reasons were enrolled in this study. Multivariate logistic regression models were used to evaluate the correlation of VAI and LAP with the risk of ICAS. In total, 845 patients were included in the study. The prevalence of ICAS gradually increased in females and in all patients with advancing tertiles of VAI or LAP. After adjusting for potential risks, both the VAI and LAP were related to ICAS in females [VAI: odds ratio (OR) = 3.25, 95% confidence interval (95%CI) = 1.17-9.03, P = 0.024; LAP: OR = 4.11, 95%CI = 1.39-12.12, P = 0.011; tertiles 3 vs. 1]. The sensitivity, specificity, and positive predictive value (PPV) were 74.7%, 45.5%, and 84.4% for VAI (cut-off: 1.71) and 79.3%, 40.5%, and 84.1% for LAP (cut-off: 23.99). The same relationships in males were not significant. Both VAI and LAP were closely associated with an increased risk of ICAS in middle-aged and elderly Chinese females.

Indexed as

Lipid Accumulation ProductAgedChinaFemaleHumansIntracranial ArteriosclerosisLogistic ModelsMaleMiddle AgedObesity, AbdominalPrevalenceSensitivity and SpecificitySex Factors

Identifiers

PMID28801558
PMCPMC5554161
OpenAlexW2743181681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.