Evidence map›Paper›PMID 28801530›Full record

ArticleGenetics2017

Rhythmic Behavior Is Controlled by the SRm160 Splicing Factor in

Esteban J Beckwith, Carlos E Hernando, Sofía Polcowñuk, Agustina P Bertolin, Estefania Mancini, M Fernanda Ceriani, Marcelo J Yanovsky

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. eLife · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Esteban J BeckwithLaboratorio de Genómica Comparativa del Desarrollo Vegetal, Fundación Instituto Leloir, Instituto de Investigeciones Bioquimicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina.ORCID 0000-0002-3373-1833
Carlos E HernandoLaboratorio de Genómica Comparativa del Desarrollo Vegetal, Fundación Instituto Leloir, Instituto de Investigeciones Bioquimicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina.
Sofía PolcowñukLaboratorio de Genética del Comportamiento, Fundación Instituto Leloir, Instituto de Investigeciones Bioquimicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina.
Agustina P BertolinLaboratorio de Ciclo Celular y Estabilidad Genómica, Fundación Instituto Leloir, Instituto de Investigaciones Bioquímica de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina.ORCID 0000-0002-4808-8254
Estefania ManciniLaboratorio de Genómica Comparativa del Desarrollo Vegetal, Fundación Instituto Leloir, Instituto de Investigeciones Bioquimicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina.
M Fernanda CerianiLaboratorio de Genética del Comportamiento, Fundación Instituto Leloir, Instituto de Investigeciones Bioquimicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina fceriani@leloir.org.ar myanovsky@leloir.org.ar.ORCID 0000-0001-8945-3070
Marcelo J YanovskyLaboratorio de Genómica Comparativa del Desarrollo Vegetal, Fundación Instituto Leloir, Instituto de Investigeciones Bioquimicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina fceriani@leloir.org.ar myanovsky@leloir.org.ar.ORCID 0000-0002-1890-0571
Consejo Nacional de Investigaciones Científicas y Técnicas · ARFundación Instituto Leloir · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian clocks organize the metabolism, physiology, and behavior of organisms throughout the day-night cycle by controlling daily rhythms in gene expression at the transcriptional and post-transcriptional levels. While many transcription factors underlying circadian oscillations are known, the splicing factors that modulate these rhythms remain largely unexplored. A genome-wide assessment of the alterations of gene expression in a null mutant of the alternative splicing regulator SR-related matrix protein of 160 kDa (SRm160) revealed the extent to which alternative splicing impacts on behavior-related genes. We show that

Indexed as

Circadian RhythmLocomotionAnimalsBrainDrosophila melanogasterDrosophila ProteinsNeuronsPeriod Circadian ProteinsRNA SplicingRNA Splicing FactorsDrosophila ProteinsPeriod Circadian ProteinsPER protein, DrosophilaRNA Splicing Factorsalternative splicingbehaviorcircadian rhythmsDrosophila melanogasterlocomotor activitySRm160 Splicing Factor

Identifiers

PMID28801530
PMCPMC5629326
OpenAlexW2743757702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.