Evidence map›Paper›PMID 28801526›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2017

An update on hormone therapy in postmenopausal women: mini-review for the basic scientist.

Virginia M Miller, S Mitchell Harman

Abstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Innovations in Peripheral Nerve Regeneration.Bioengineering (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Review
  8. CaFrontiers in cellular neuroscience · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Sex-specific effects of high-fat diet on cognitive impairment in a mouse model of VCID.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Virginia M MillerDepartments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota; and miller.virginia@mayo.edu.
S Mitchell HarmanKronos Longevity Research Institute and the Phoenix Veterans Administration Health Care System, Phoenix, Arizona.

Funding

Sex-specific Risk for Vascular Dysfunction and Cognitive DeclineP50AG044170 · NIA · MAYO CLINIC ROCHESTER · PI MILLER, VIRGINIA M · 2012 to 2017
$6.1M
NIA NIH HHS P50 AG044170
6 · The paper itself

Abstract

The worlds of observational, clinical, and basic science collided in 2002 with the publication of results of the Women's Health Initiative (WHI), a large-scale, prospective, blinded, randomized-controlled trial designed to provide evidence regarding use of hormone treatment to prevent cardiovascular disease in menopausal women. The results of the WHI dramatically changed clinical practice, negatively impacted funding for hormone research, and left scientists to unravel the "why" of the results. Now over a decade and a half since the initial publication of the WHI results, basic and clinical scientists often do not interpret the results of the WHI with the precision needed to move the science forward. This review will

Indexed as

Biomedical ResearchPostmenopauseAge FactorsAnimalsComorbidityDrug Administration ScheduleDrug CompoundingEstrogen Replacement TherapyEstrogensEvidence-Based MedicineFemaleHumansPatient SafetyPractice Guidelines as TopicRisk FactorsTreatment OutcomeEstrogens17β-estradiolconjugated equine estrogenEarly Versus Late Intervention TrialKronos Early Estrogen Prevention Studytiming hypothesisWomen’s Health Initiative

Identifiers

PMID28801526
PMCPMC5792205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.