Evidence map›Paper›PMID 28801429›Full record

Trial reportBMJ open2017

Multicentric randomised study of

Marcis Leja, Jin Young Park, Raul Murillo, Inta Liepniece-Karele, Sergejs Isajevs, Ilze Kikuste, Dace Rudzite, Petra Krike, Sergei Parshutin, Inese Polaka and 6 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02047994 (Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02047994 phase4recruitingnot on this map

Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality

TypeinterventionalSponsorInternational Agency for Research on CancerRan2013 to 2035Enrolled30,000ConditionsHelicobacter Pylori Infections, Atrophic Gastritis, Gastric CancerArmsTriple therapy
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Helicobacter pylori eradication for the prevention of gastric neoplasia.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Positive association between anti-Helicobacter pylori IgG antibody titers and atrophic gastritis in a Latvian cohort.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  7. Review
  8. Review
  9. Current and Future Perspectives on the Management ofAntibiotics (Basel, Switzerland) · 2024
    Review
  10. Helicobacter pylori infection.Nature reviews. Disease primers · 2023
    Review
  11. Article
  12. Diagnostic and therapeutic recommendations onPrzeglad gastroenterologiczny · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Marcis LejaInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.ORCID http://orcid.org/0000-0002-0319-8855
Jin Young ParkPrevention and Implementation Group, International Agency for Research on Cancer, Lyon, France.
Raul MurilloPrevention and Implementation Group, International Agency for Research on Cancer, Lyon, France.
Inta Liepniece-KareleInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Sergejs IsajevsInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Ilze KikusteInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Dace RudziteInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Petra KrikeInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Sergei ParshutinInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Inese PolakaInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Arnis KirsnersInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Daiga SantareInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Valdis FolkmanisInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Ilva DauguleInstitute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.
Martyn PlummerInfection and Cancer Epidemiology Group, International Agency for Research on Cancer, Lyon, France.
Rolando HerreroPrevention and Implementation Group, International Agency for Research on Cancer, Lyon, France.
Riga East University Hospital · LVCentre international de recherche sur le cancer · FRUniversity of Latvia · LVRiga Technical University · LV

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionPopulation-based eradication of METHODS AND ANALYSIS: Individuals are recruited from general population (50% men) in areas with high gastric cancer risk in Europe and undergo detailed lifestyle and medical history questionnaire before being randomly allocated to intervention or control groups. The intervention group undergoes ETHICS AND DISSEMINATION: The study was approved by the respective ethics committees. An independent Data Safety and Monitoring Board has been established. The findings will be published in peer-reviewed journals and presented at scientific meetings. TRIAL REGISTRATION NUMBER: NCT02047994.

Indexed as

AdultAnti-Bacterial AgentsEuropeFemaleGastroscopyHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedMortalityPepsinogen APrecancerous ConditionsResearch DesignStomachStomach NeoplasmsAnti-Bacterial AgentsPepsinogen AEradicationGastric CancerH. PyloriPepsinogenPreventionRandomised Study

Identifiers

PMID28801429
PMCPMC5724070
OpenAlexW2743548181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.