Evidence map›Paper›PMID 28801359›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

CCR7 Deficiency Allows Accelerated Clearance of

Lin-Xi Li, Jasmine C Labuda, Denise M Imai, Stephen M Griffey, Stephen J McSorley

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. CXCR6 marks polyfunctional effector CD4 T cells required for anti-bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lin-Xi LiDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR 72205; lxli@uams.edu.
Jasmine C LabudaCenter for Comparative Medicine, Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616; and.
Denise M ImaiComparative Pathology Laboratory, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616.ORCID 0000-0003-0667-2054
Stephen M GriffeyComparative Pathology Laboratory, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616.
Stephen J McSorleyCenter for Comparative Medicine, Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616; and.
University of California, Davis · USUniversity of Arkansas for Medical Sciences · US

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
Animal Models of Infectious Diseases Training ProgramT32AI060555 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI MCSORLEY, STEPHEN J · 2004 to 2025
$3.3M
CD4 T cell responses to Chlamydia infectionR01AI103422 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCSORLEY, STEPHEN J · 2016 to 2019
$1.5M
Generation of a TCR transgenic mouse to study Chlamydia genital tract infectionR21AI117303 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCSORLEY, STEPHEN J · 2015 to 2016
$422k
NIAID NIH HHS R01 AI103422NIAID NIH HHS R21 AI117303NIAID NIH HHS T32 AI060555NIGMS NIH HHS P20 GM103625
6 · The paper itself

Abstract

Immune mechanisms responsible for pathogen clearance from the female reproductive tract (FRT) are incompletely defined; in particular, the contribution of lymphocyte trafficking to this process is unclear. CCR7-deficient mice have profoundly altered lymphocyte recirculation and display ectopic formation of lymphocyte aggregates within mucosal nonlymphoid tissues, including the FRT. In this study, we investigated how altered lymphocyte distribution in CCR7-deficient mice would affect host responses to

Indexed as

AnimalsAntibodies, BacterialCD4-Positive T-LymphocytesCell MovementChlamydia InfectionsChlamydia muridarumFemaleImmunoglobulin AInflammationLymph NodesMiceMice, KnockoutReceptors, CCR7Reproductive Tract InfectionsTh17 CellsTh1 CellsAntibodies, BacterialCcr7 protein, mouseImmunoglobulin AReceptors, CCR7

Identifiers

PMID28801359
PMCPMC5605455
OpenAlexW2745149346

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.