Evidence map›Paper›PMID 28801196›Full record

ArticleThe Journal of allergy and clinical immunology2018

Prenatal fine particulate exposure and early childhood asthma: Effect of maternal stress and fetal sex.

Alison Lee, Hsiao-Hsien Leon Hsu, Yueh-Hsiu Mathilda Chiu, Sonali Bose, Maria José Rosa, Itai Kloog, Ander Wilson, Joel Schwartz, Sheldon Cohen, Brent A Coull and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 3 pooled it
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 3 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The impact of prenatal exposure to PMEnvironmental science and pollution research international · 2020
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Early Life Exposure to Air Pollutants and Childhood Asthma.Current allergy and asthma reports · 2026
    Review
  8. Multi-Tree Model for Precision Environmental Health with Longitudinally Assessed Mixture Exposure.Journal of the Royal Statistical Society. Series C, Applied statistics · 2026
    Article
  9. Article
  10. Update on environmental determinants of allergic diseases.The Journal of allergy and clinical immunology · 2026
    Review
  11. Review
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Wildfire Seasons, Prenatal PMACS ES&T air · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Alison LeeDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Hsiao-Hsien Leon HsuDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY.
Yueh-Hsiu Mathilda ChiuDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY.
Sonali BoseDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Maria José RosaDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY.
Itai KloogFaculty of Humanities and Social Sciences, Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Ander WilsonDepartment of Statistics, Colorado State University, Fort Collins, Colo.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Sheldon CohenDepartment of Psychology, Carnegie Mellon University, Pittsburgh, Pa.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Mass.
Robert O WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: rosalind.wright@mssm.edu.
Mount Sinai Hospital · USIcahn School of Medicine at Mount Sinai · USHarvard University · USBen-Gurion University of the Negev · ILCarnegie Mellon University · USColorado State University · US

Funding

Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
GRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
Stress, Environment, and Genetics in Urban AsthmaR01HL080674 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2005 to 2014
$7.0M
MULTI-LEVEL ANALYSIS OF URBAN CHILDHOOD ASTHMA RISKR01ES010932 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2000 to 2004
$3.0M
Air pollution, stress and urban child developmentR01MD006086 · NIMHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2010 to 2014
$2.2M
Asthma Coalition on Community, Environment and StressU01HL072494 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2002 to 2003
$1.5M
Prenatal PM2.5 and programming of respiratory outcomes: Placental biomarkers and effect modification by stressK23HL135349 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LEE, ALISON G · 2017 to 2021
$884k
NHLBI NIH HHS K23 HL135349NHLBI NIH HHS R01 HL080674NHLBI NIH HHS U01 HL072494NICHD NIH HHS T32 HD049311NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES010932NIEHS NIH HHS T32 ES007142NIH HHS UH3 OD023337NIMHD NIH HHS R01 MD006086
6 · The paper itself

Abstract

backgroundThe impact of prenatal ambient air pollution on child asthma may be modified by maternal stress, child sex, and exposure dose and timing.

objectiveWe prospectively examined associations between coexposure to prenatal particulate matter with an aerodynamic diameter of less than 2.5 microns (PM

methodsDaily PM

resultsBayesian distributed lag interaction models identified a critical window of exposure (19-23 weeks' gestation, cumulative odds ratio, 1.15; 95% CI, 1.03-1.26; per interquartile range [1.7 μg/m

conclusionsPrenatal PM

Indexed as

Air PollutantsAir PollutionAsthmaBayes TheoremChildFemaleGestational AgeHumansHypersensitivityMaternal ExposureMothersParticulate MatterPregnancyPrenatal Exposure Delayed EffectsProspective StudiesSexAir PollutantsParticulate Matterambient air pollutionchildhood asthmanegative life eventsParticulate matterprenatal stresssex- and temporal-specific effects

Identifiers

PMID28801196
PMCPMC5803480
OpenAlexW2744554114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.