Evidence map›Paper›PMID 28800377›Full record

ArticleBritish journal of pharmacology2017

Antidote to cannabinoid intoxication: the CB

Gareth Pryce, David Baker

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Tetrahydrocannabivarin is Not Tetrahydrocannabinol.Cannabis and cannabinoid research · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. CannabinoidJournal of neural transmission (Vienna, Austria : 1996) · 2020
    Review
  11. Article
  12. Antidote to cannabinoid intoxication: the CBBritish journal of pharmacology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gareth PryceBlizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
David BakerBlizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-8872-8711
Queen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCannabis is a recreational drug leading to intoxication, following stimulation of cannabinoid CB EXPERIMENTAL APPROACH: Cannabimimetic effects, measured by the hypothermic response following sedation and hypomotility, were induced by the synthetic CB KEY

resultsIn this study, the CNS-related cannabimimetic effects, as measured by the hypothermic effect, induced by the CB CONCLUSIONS AND IMPLICATIONS: Cannabinoid receptor antagonists have been widely used and so may provide an acceptable single-dose antidote to cannabinoid intoxication. This use may save human life, where the life-threatening effects are mediated by cannabinoid receptors and not off-target influences of the synthetic cannabinoids or non-cannabinoids within the recreational drug mixture.

Indexed as

AnimalsAntidotesCannabinoid Receptor AgonistsDrug Inverse AgonismFemaleHypothermiaMiceMice, BiozziNaphthalenesPiperidinesPyrazolesReceptor, Cannabinoid, CB1AM 251AntidotesCannabinoid Receptor Agonistsnaphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanoneNaphthalenesPiperidinesPyrazolesReceptor, Cannabinoid, CB1

Identifiers

PMID28800377
PMCPMC5647190
OpenAlexW2744391892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.