Evidence map›Paper›PMID 28800263›Full record

ReviewInternational reviews of immunology2017

MicroRNA mediated regulation of immunity against gram-negative bacteria.

Jonathon Keck, Rishein Gupta, Lane K Christenson, Bernard P Arulanandam

Open access · greenAbstract readReview
In one paragraph

Review in International reviews of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Modulation of Immune Response toFrontiers in cellular and infection microbiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonathon Kecka South Texas Center for Emerging Infectious Diseases and Center of Excellence in Infection Genomics , University of Texas at San Antonio , One UTSA Circle, San Antonio , TX.
Rishein Guptaa South Texas Center for Emerging Infectious Diseases and Center of Excellence in Infection Genomics , University of Texas at San Antonio , One UTSA Circle, San Antonio , TX.
Lane K Christensonb Department of Molecular and Integrative Physiology , University of Kansas Medical Center , Kansas City , Kansas.
Bernard P Arulanandama South Texas Center for Emerging Infectious Diseases and Center of Excellence in Infection Genomics , University of Texas at San Antonio , One UTSA Circle, San Antonio , TX.
Texas Center for Infectious Disease · USUniversity of Kansas Medical Center · US

Funding

MicroRNA Regulation of Ovarian FunctionR01HD061580 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI CHRISTENSON, LANE K. · 2010 to 2014
$1.5M
The Contribution of MicroRNA-182 in Genital Chlamydia trachomatis InfectionR03AI117714 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI ARULANANDAM, BERNARD PRAGASH · 2016 to 2017
$147k
NIAID NIH HHS R03 AI117714NICHD NIH HHS R01 HD061580
6 · The paper itself

Abstract

Evidence over the last couple decades has comprehensively established that short, highly conserved, non-coding RNA species called microRNA (miRNA) exhibit the ability to regulate expression and function of host genes at the messenger RNA (mRNA) level. MicroRNAs play key regulatory roles in immune cell development, differentiation, and protective function. Intrinsic host immune response to invading pathogens rely on intricate orchestrated events in the development of innate and adaptive arms of immunity. We discuss the involvement of miRNAs in regulating these processes against gram negative pathogens in this review.

Indexed as

Adaptive ImmunityAnimalsCell DifferentiationGram-Negative BacteriaGram-Negative Bacterial InfectionsHost-Parasite InteractionsHumansImmunity, InnateImmunomodulationMicroRNAsMicroRNAsBacteriagram negativehost immunitymicroRNAs

Identifiers

PMID28800263
PMCPMC6904929
OpenAlexW2743476335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.