ReviewThe ISME journal2017
Network analysis of gut microbiota literature: an overview of the research landscape in non-human animal studies.
Review in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed.
- The elephant (bird) in the room: unknown mechanisms and unresolved impacts of low DNA yields in avian microbiome research.Animal microbiome · 2026Article
- A lagging recovery: the delayed restoration of gut microbial diversity in Rhinolophus sinicus post-hibernation.Animal microbiome · 2026Article
- Article
- Associations and interactions between prokaryotes and other gut biota in non-human primates.Primates; journal of primatology · 2026Review
- Dynamics of Gut Microbiota in Japanese Tits (Microorganisms · 2025Article
- Uncovering the gut microbiome and antibiotic resistome of mammals on the Tibetan Plateau.Science China. Life sciences · 2025Article
- The Impact of Whole-Animal Fluid Preservation on the Observed Gut Microbiome of Vertebrates: Implications for the Use of Museum Specimens in Microbiome Research.Molecular ecology resources · 2025Article
- Article
- Review
- Pondering Ponds: Exploring Correlations Between Cloacal Microbiota and Blood Metabolome in Freshwater Turtles.Microbial ecology · 2025Article
- Gut Microecology of Four Sympatric Desert Rodents Varies by Diet.Ecology and evolution · 2025Article
- Geology correlates with gut microbial community composition in the Mountainsnails (Oreohelicidae:PeerJ · 2025Article
- Long-Read Sequencing Revealing the Effectiveness of Captive Breeding Strategy for Improving the Gut Microbiota of Spotted Seal (Phoca largha).Marine biotechnology (New York, N.Y.) · 2024Article
- Manipulating a host-native microbial strain compensates for low microbial diversity by increasing weight gain in a wild bird population.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The Response of Murine Gut Microbiome in the Presence of AlteredInternational journal of molecular sciences · 2024Article
- Genetic hypogonadal (Gnrh1bioRxiv : the preprint server for biology · 2024Article
- Geographical distribution and species variation of gut microbiota in small rodents from the agro-pastoral transition ecotone in northern China.Ecology and evolution · 2024Article
- Something in the water: aquatic microbial communities influence the larval amphibian gut microbiota, neurodevelopment and behaviour.Proceedings. Biological sciences · 2024Article
- Influence of host phylogeny and water physicochemistry on microbial assemblages of the fish skin microbiome.FEMS microbiology ecology · 2024Article
- Stochastic Assembly Increases the Complexity and Stability of Shrimp Gut Microbiota During Aquaculture Progression.Marine biotechnology (New York, N.Y.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A wealth of human studies have demonstrated the importance of gut microbiota to health. Research on non-human animal gut microbiota is now increasing, but what insight does it provide? We reviewed 650 publications from this burgeoning field (2009-2016) and determined that animals driving this research were predominantly 'domestic' (48.2%), followed by 'model' (37.5%), with least studies on 'wild' (14.3%) animals. Domestic studies largely experimentally perturbed microbiota (81.8%) and studied mammals (47.9%), often to improve animal productivity. Perturbation was also frequently applied to model animals (87.7%), mainly mammals (88.1%), for forward translation of outcomes to human health. In contrast, wild animals largely characterised natural, unperturbed microbiota (79.6%), particularly in pest or pathogen vectoring insects (42.5%). We used network analyses to compare the research foci of each animal group: 'diet' was the main focus in all three, but to different ends: to enhance animal production (domestic), to study non-infectious diseases (model), or to understand microbiota composition (wild). Network metrics quantified model animal studies as the most interdisciplinary, while wild animals incorporated the fewest disciplines. Overall, animal studies, especially model and domestic, cover a broad array of research. Wild animals, however, are the least investigated, but offer under-exploited opportunities to study 'real-life' microbiota.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.