Evidence map›Paper›PMID 28799997›Full record

ReviewCurrent opinion in HIV and AIDS2017

Epidemiology of ischemic heart disease in HIV.

Virginia A Triant, Steven K Grinspoon

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in HIV and AIDS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Examining Depression as a Risk Factor for Cardiovascular Disease in People with HIV: A Systematic Review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023
    Pooled it
  2. Article
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  6. Review
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  15. [Biomolecules · 2020
    Article
  16. Observational
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  18. Review
  19. Molecular Imaging of Vascular Calcification withInternational journal of molecular sciences · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Virginia A TriantaDivision of General Internal Medicine bDivision of Infectious Diseases cProgram in Nutritional Metabolism, Massachusetts General Hospital, Boston, Massachusetts, USA.
Steven K Grinspoon
GTx (United States) · USMassachusetts General Hospital · US

Funding

REPRIEVE COVID-19 Administrative SupplementU01HL123336 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI DOUGLAS, PAMELA SUSAN, GRINSPOON, STEVEN K. · 2014 to 2021
$52.4M
Optimizing Cardiovascular Risk Prediction in HIVR01HL132786 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI D'AGOSTINO, RALPH B, TRIANT, VIRGINIA ATHENA · 2017 to 2020
$3.5M
NHLBI NIH HHS R01 HL132786NHLBI NIH HHS U01 HL123336
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to summarize and synthesize recent data on the risk of ischemic heart disease (IHD) in HIV-infected individuals. RECENT

findingsRecent studies in the field demonstrate an increasing impact of cardiovascular disease (CVD) on morbidity and mortality in HIV relative to AIDS-related diagnoses. Studies continue to support an approximately 1.5 to two-fold increased risk of IHD conferred by HIV, with specific risk varying by sex and virologic/immunologic status. Risk factors include both traditional CVD risk factors and novel, HIV-specific factors including inflammation and immune activation. Specific antiretroviral therapy (ART) drugs may increase CVD risk, yet the net effect of ART with viral suppression is beneficial with regard to CVD risk. Management of cardiovascular risk and prevention of CVD is complex, because current general population strategies target traditional CVD risk factors only. Extensive investigation is being directed at developing tailored CVD risk prediction algorithms and interventions to reduce CVD risk in HIV. SUMMARY: Increased IHD risk is a significant clinical and public health challenge in HIV. The development and application of HIV-specific interventions to manage CVD risk factors and reduce CVD risk will improve the long-term health of this ageing population.

Indexed as

Anti-Retroviral AgentsDisease ManagementHIV InfectionsHumansMyocardial IschemiaRisk AssessmentRisk FactorsRisk ManagementAnti-Retroviral Agents

Identifiers

PMID28799997
PMCPMC5776691
OpenAlexW2742878865

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.