Evidence map›Paper›PMID 28799824›Full record

ArticleInternational journal of STD & AIDS2018

High prevalence of asymptomatic sexually transmitted infections among human immunodeficiency virus-infected pregnant women in a low-income South African community.

Maanda Mudau, Remco P Peters, Lindsey De Vos, Dawie H Olivier, Dvora J Davey, Edwin S Mkwanazi, James A McIntyre, Jeffrey D Klausner, Andrew Medina-Marino

Open access · greenAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 64 citations in OpenAlex.

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  11. Investigating causes of the high prevalence of sexually transmitted infections in Du Noon.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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  20. Significant Associations betweenInfectious diseases in obstetrics and gynecology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Maanda Mudau1 Research Unit, Foundation for Professional Development, Pretoria, South Africa.ORCID 0000-0003-0697-2460
Remco P Peters2 Anova Health Institute, Johannesburg, South Africa.
Lindsey De Vos1 Research Unit, Foundation for Professional Development, Pretoria, South Africa.
Dawie H Olivier1 Research Unit, Foundation for Professional Development, Pretoria, South Africa.ORCID 0000-0001-7654-1434
Dvora J Davey4 Department of Epidemiology and Biostatics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Edwin S Mkwanazi1 Research Unit, Foundation for Professional Development, Pretoria, South Africa.
James A McIntyre2 Anova Health Institute, Johannesburg, South Africa.
Jeffrey D Klausner5 David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Andrew Medina-Marino1 Research Unit, Foundation for Professional Development, Pretoria, South Africa.
Foundation for Professional Development · ZAUniversity of Cape Town · ZAAnova Health Institute · ZAUniversity of California, Los Angeles · US

Funding

Syphilis Immunology and Biology to Improve Clinical Management and Vaccine DesignR01AI139265 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jeffrey David Klausner · 2018 to 2026
$4.8M
Pilot Study of STI Screening and Treatment for PMTCTR21HD084274 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KLAUSNER, JEFFREY DAVID, MEDINA-MARINO, ANDREW · 2015 to 2016
$352k
NIAID NIH HHS R01 AI139265NICHD NIH HHS R21 HD084274PEPFAR
6 · The paper itself

Abstract

There is a lack of evidence on the burden of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) among HIV-infected pregnant women in South Africa. We conducted a cross-sectional analysis of HIV-infected pregnant women in two healthcare facilities in a South African township to determine the prevalence of CT, NG and TV. HIV-infected pregnant women were recruited during the first antenatal care visit for their current pregnancy and requested to self-collect vulvovaginal swab specimens. Specimens were tested for CT, NG and TV using the Xpert® assay (Cepheid, Sunnyvale, CA). Of 247 tested for CT, NG and TV, 47.8% tested positive for at least one organism; CT = 36.8%, TV = 23.9%, NG = 6.9%. Forty three (17.4%) had multiple infections, of which 42 included CT as one of the infecting organisms. Of the 118 participants who tested positive for at least one sexually transmitted infection (STI), 23.7% reported STI-like symptoms. Among women who tested positive for CT, 29.7% reported symptoms while 47.1 and 27.1% of those who tested positive for NG and TV, respectively, reported symptoms. The high STI prevalence coupled with the low symptom prevalence among infected individuals justifies the use of diagnostic screening approaches rather than syndromic management of STIs in this setting.

Indexed as

AdultAsymptomatic InfectionsChlamydia InfectionsChlamydia trachomatisCross-Sectional StudiesFemaleGonorrheaHIV InfectionsHumansNeisseria gonorrhoeaePovertyPregnancyPregnancy Complications, InfectiousPrevalenceSexually Transmitted DiseasesSocioeconomic FactorsChlamydiagonorrhoeaHIVscreeningtrichomoniasis

Identifiers

PMID28799824
PMCPMC6879095
OpenAlexW2743604568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.