Trial reportJournal of the American Geriatrics Society2017
Device-Measured Physical Activity As a Predictor of Disability in Mobility-Limited Older Adults.
Trial report in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Reducing Sedentary Time After Knee Replacement Using a Multicomponent mHealth Intervention: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Feasibility of unsupervised, home-based leg heat therapy in older adults: a pilot, sham-controlled trial.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Trial
- Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults.Journal of the American Geriatrics Society · 2019Trial
- Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study.Journal of the American Heart Association · 2017Trial
- Multimodal data-based human motion intention prediction using adaptive hybrid deep learning network for movement challenged person.Scientific reports · 2024Article
- A social media game to increase physical activity among older adult women: protocol of a randomized controlled trial to evaluate CHALLENGE.BMC public health · 2024Article
- Article
- Multidisciplinary understanding of modifiable physical disability risk factors for health professionals: A scoping review protocol.PloS one · 2024Article
- Indoor Mobility, Frailty, and Disability in Community-Dwelling Older Adults: A Mediation Model.International journal of environmental research and public health · 2022Article
- An Intervention of 12 Weeks of Nordic Walking and Recreational Walking to Improve Cardiorespiratory Capacity and Fitness in Older Adult Women.Journal of clinical medicine · 2022Article
- Variability in Hourly Activity Levels: Statistical Noise or Insight Into Older Adult Frailty?The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- An Optimal Self-Report Physical Activity Measure for Older Adults: Does Physical Function Matter?Journal of aging and physical activity · 2021Article
- Effect of Inpatient and Outpatient Pneumonia on Mobility Disability, Gait Speed, and Physical Activity in Older Adults.Journal of clinical medicine · 2021Article
- Accelerometer-Measured Sedentary Patterns are Associated with Incident Falls in Older Women.Journal of the American Geriatrics Society · 2021Article
- Evaluation of Light Physical Activity Measured by Accelerometry and Mobility Disability During a 6-Year Follow-up in Older Women.JAMA network open · 2021Article
- Stand When You Can: development and pilot testing of an intervention to reduce sedentary time in assisted living.BMC geriatrics · 2020Review
- Physical activity is associated with functional capacity of older women with osteosarcopenic obesity: 24-month prospective study.European journal of clinical nutrition · 2020Article
- Bibliometric analysis of core journals which publish articles of physical therapy on aging.Physical therapy research · 2020Review
- Article
- Physical Activity Intensity Cut-Points for Wrist-Worn GENEActiv in Older Adults.Frontiers in sports and active living · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
objectivesTo examine associations between objectively measured physical activity (PA) and incidence of major mobility disability (MMD) and persistent MMD (PMMD) in older adults in the Lifestyle Interventions and Independence for Elders (LIFE) Study.
designProspective cohort of individuals aged 65 and older undergoing structured PA intervention or health education.
settingThe LIFE Study was a multicenter (eight sites) randomized controlled trial designed to compare the efficacy of a long-term structured PA intervention with that of a health education (HE) program in reducing the incidence of MMD in mobility-limited older adults.
participantsLIFE Study participants (n = 1,590) had a mean age±standard deviation of 78.9 ± 5.2, low levels of PA, and measured mobility-relevant functional impairment at baseline. MEASUREMENTS: Activity data were collected using hip-worn 7-day accelerometers at baseline and 6, 12, and 24 months after randomization to test for associations with incident MMD and PMMD (≥2 consecutive instances of MMD).
resultsAt baseline, every 30 minutes spent being sedentary (<100 accelerometry counts per minute) was associated with higher rate of subsequent MMD (10%) and PMMD (11%) events. Every 500 steps taken was associated with lower rate of MMD (15%) and PMMD (18%). Similar associations were observed when fitting accelerometry-based PA as a time-dependent variable.
conclusionAccelerometry-based PA levels were strongly associated with MMD and PMMD events in older adults with limited mobility. These results support the importance of daily PA and lower amounts of sedentary time levels in this population and suggest that accelerometry may be a useful tool for assessing risk of mobility disability.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.