Evidence map›Paper›PMID 28799121›Full record

ArticleInternational urology and nephrology2017

3-T multiparametric MRI characteristics of prostate cancer patients suspicious for biochemical recurrence after primary focal cryosurgery (hemiablation).

Michael Kongnyuy, Daniel M Halpern, Corinne C Liu, Kaitlin E Kosinski, David J Habibian, Anthony T Corcoran, Aaron E Katz

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Article in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael KongnyuyDepartment of Urology, NYU-Winthrop University, 1300 Franklin Ave, Garden City, Mineola, NY, USA. speeditomike@gmail.com.ORCID http://orcid.org/0000-0001-5727-5775
Daniel M HalpernDepartment of Urology, NYU-Winthrop University, 1300 Franklin Ave, Garden City, Mineola, NY, USA.
Corinne C LiuDepartment of Radiology, NYU-Winthrop University, Mineola, NY, USA.
Kaitlin E KosinskiDepartment of Urology, NYU-Winthrop University, 1300 Franklin Ave, Garden City, Mineola, NY, USA.
David J HabibianSt George's University School of Medicine, St. George's, Grenada.
Anthony T CorcoranDepartment of Urology, NYU-Winthrop University, 1300 Franklin Ave, Garden City, Mineola, NY, USA.
Aaron E KatzDepartment of Urology, NYU-Winthrop University, 1300 Franklin Ave, Garden City, Mineola, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to report on multiparametric MRI (mpMRI) characteristics of post-primary focal cryosurgery (PFC) patients suspected of biochemical recurrence (BCR) by the Phoenix criteria.

methodsWe retrospectively reviewed all patients at our institution who had undergone PFC. Prostate-specific antigen nadir was determined using 2 or more post-PFC values. Suspicion of BCR was determined using the Phoenix criteria (nadir + 2 ng/ml). At the discretion of the physician, pre-and post-PFC 3-T mpMRIs were obtained and in a few cases biopsies were performed.

resultsNinety (58.4%) of 154 consecutive patients who underwent PFC were included in our analysis and had a median (range) age and prostate volume of 66.5 (48-82) years and 40.5 (16-175) ml, respectively. Of those suspected of BCR (37/90, 41.1%), with a median time to BCR of 19.9 (7.0-38.5) months, 27 patients (73.0%) underwent a post-PFC mpMRI. Twenty-two (81.5%) of these mpMRIs were found with 24 suspicious lesions. A considerable number (9/24, 37.5%) of these lesions were located in the central gland of the prostate. Seven of 24 lesions exhibited adverse mpMRI characteristic; 4 (16.7%) had capsular contact, 2 (8.2%) showed frank extracapsular extension, and 1 (4.2%) showed seminal vesicle invasion. Five (45.5%) of 11 patients with positive post-PFC mpMRIs were positive on biopsy (4/5, 80% were clinically significant prostate cancer).

conclusionPost-PFC mpMRI, at Phoenix suspicion of BCR, may help identify a significant number of patients failing post-PFC.

Indexed as

AgedAged, 80 and overBiopsyCryosurgeryHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm InvasivenessNeoplasm Recurrence, LocalProstateProstate-Specific AntigenProstatic NeoplasmsRetrospective StudiesProstate-Specific AntigenBiochemical recurrenceMultiparametric MRIPrimary focal cryosurgeryProstate cancer

Identifiers

PMID28799121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.