ArticleEnvironmental science and pollution research international2017
Association of lead exposure with cardiovascular risk factors and diseases in Chinese adults.
Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Spirulina as a natural shield: a comprehensive review of its protective effects against lead toxicity.Archives of toxicology · 2025Review
- Evaluating the association between opium abuse, blood lead levels, and the complexity of coronary artery disease.Physiological reports · 2024Article
- Association of Blood Heavy Metal Exposure with Atherosclerotic Cardiovascular Disease (ASCVD) Among White Adults: Evidence from NHANES 1999-2018.Biological trace element research · 2023Article
- Blood Lead Level Is Associated with Visceral Adipose Dysfunction in Patients with Type 2 Diabetes.Biological trace element research · 2023Article
- Soil and water pollution and human health: what should cardiologists worry about?Cardiovascular research · 2023Review
- Disturbed Ratios between Essential and Toxic Trace Elements as Potential Biomarkers of Acute Ischemic Stroke.Nutrients · 2023Article
- Metabolome-Wide Association Study of Multiple Plasma Metals with Serum Metabolomic Profile among Middle-to-Older-Aged Chinese Adults.Environmental science & technology · 2022Article
- Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia.Toxics · 2022Article
- Mapping the Morbidity Risk Associated with Coal Mining in Queensland, Australia.International journal of environmental research and public health · 2022Article
- Lead exposure is non-linearly associated with subclinical myocardial injury in the general population without cardiovascular disease.Frontiers in public health · 2022Article
- Blood lead level in Chinese adults with and without coronary artery disease.Journal of geriatric cardiology : JGC · 2021Article
- Lead (Pb) exposure and heart failure risk.Environmental science and pollution research international · 2021Review
- Article
- Famine exposure in early life is associated with visceral adipose dysfunction in adult females.European journal of nutrition · 2019Article
- Association between blood lead level and subsequent Alzheimer's disease mortality.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Association of CALM1 rs3179089 Polymorphism with Ischemic Stroke in Chinese Han Population.Neuromolecular medicine · 2018Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
We aimed to determine whether lead exposure was associated with cardiovascular diseases (CVD) and risk factors in Chinese adults. Five thousand three hundred and forty-eight subjects were enrolled from 16 sites in China. Blood lead level (BLL) was measured by atomic absorption spectrometry. Cardiovascular diseases included coronary heart disease, stroke, and myocardial infarction. Cardiovascular risk factors included body mass index (BMI), fasting plasma glucose (FPG), lipid profile, and blood pressure. We found that 5.9% of the study population had prevalent CVD. Medians (interquartile range) of BLLs were 44.00 μg/L (29.00-62.48) for men and 37.70 μg/L (25.00-54.60) for women. The prevalence of CVD gradually and markedly increased with increasing BLL quartiles in women (P for trend < 0.01), but not in men. After adjustment for age, current smoking, and drinking, BLLs were independently associated with cardiovascular risk factors including BMI, FPG, and blood pressure in women (all P < 0.05), but not in men. Binary logistic regression showed that increased quartiles of BLL were significantly and positively associated with increased odds ratio of prevalent CVD (P for trend < 0.01) in women. This association was independent of age, smoking, drinking, education, diabetes, obesity, hypertension, and lipid profile. In conclusion, BLL in the range currently considered acceptable is independently associated with CVD, which is the leading cause of death in China. Further practical and cost-effective efforts to reduce lead exposure may be warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.