ArticleCancer causes & control : CCC2017
Endometriosis and the risk of skin cancer: a prospective cohort study.
Article in Cancer causes & control : CCC, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Endometriosis and the Risk of Melanoma: A Shared Thread?Journal of obstetrics and gynaecology of India · 2024Article
- Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities.Human reproduction update · 2023Review
- Endometriosis, Psoriasis, and Psoriatic Arthritis: A Prospective Cohort Study.American journal of epidemiology · 2022Article
- HOX cluster and their cofactors showed an altered expression pattern in eutopic and ectopic endometriosis tissues.Reproductive biology and endocrinology : RB&E · 2021Article
- Genetic Relationship Between Endometriosis and Melanoma.Frontiers in reproductive health · 2021Article
- Recreational and residential sun exposure and risk of endometriosis: a prospective cohort study.Human reproduction (Oxford, England) · 2021Article
- Long-term Health Consequences of Endometriosis - Pathways and Mediation by Treatment.Current obstetrics and gynecology reports · 2020Article
- Genes' Interactions: A Major Contributor to the Malignant Transformation of Endometriosis.International journal of molecular sciences · 2019Review
- Machine Learning Classifiers for Endometriosis Using Transcriptomics and Methylomics Data.Frontiers in genetics · 2019Article
- Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis.The Journal of endocrinology · 2018Article
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 2 countries.
Funding
Abstract
purposeEndometriosis has been associated with an increased risk of skin melanoma. However, associations with other skin cancer types and how they compare with melanoma are unclear. Our objective was to prospectively investigate the relationships between endometriosis and risk of non-melanoma and melanoma skin cancers.
methodsE3N is a prospective cohort of 98,995 French women aged 40-65 years in 1990. Data on surgically confirmed endometriosis and skin cancer diagnoses were collected every 2-3 years through self-report, with skin cancer cases confirmed through pathology reports. Hazard Ratios (HR) and 95% confidence intervals (CIs) were calculated using Cox regression models.
resultsBetween 1990 and 2008, 535 melanoma, 247 squamous-cell carcinoma (SCC), and 1,712 basal-cell carcinoma (BCC) cases were ascertained. Endometriosis was associated with an increased overall risk of skin cancer (HR 1.28, 95% CI 1.05-1.55). When considering skin cancer type, endometriosis was associated with melanoma risk (HR 1.64, 95% CI 1.15-2.35), but not with SCC (HR 1.21, 95% CI 0.62-2.36) or BCC (HR 1.16, 95% CI 0.91-1.48) (non-melanoma skin cancers combined: HR 1.17, 95% CI 0.93-1.46), although no heterogeneity was detected across skin cancer types (Phomogeneity = 0.13).
conclusionThese data support an association between a personal history of endometriosis and the risk of skin cancer and suggest that the association is strongest for melanoma.
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