Evidence map›Paper›PMID 28798678›Full record

ArticleFrontiers in computational neuroscience2017

Striatal Neuropeptides Enhance Selection and Rejection of Sequential Actions.

David Buxton, Enrico Bracci, Paul G Overton, Kevin Gurney

Open access · goldAbstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. The NK1 antagonist L-733,060 facilitates sequence learning.Journal of psychopharmacology (Oxford, England) · 2023
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David BuxtonAdaptive Behaviour Research Group, Department of Psychology, The University of SheffieldSheffield, United Kingdom.
Enrico BracciAdaptive Behaviour Research Group, Department of Psychology, The University of SheffieldSheffield, United Kingdom.
Paul G OvertonAdaptive Behaviour Research Group, Department of Psychology, The University of SheffieldSheffield, United Kingdom.
Kevin GurneyAdaptive Behaviour Research Group, Department of Psychology, The University of SheffieldSheffield, United Kingdom.
University of Sheffield · GB

Funding

Medical Research Council MR/K022512/1
6 · The paper itself

Abstract

The striatum is the primary input nucleus for the basal ganglia, and receives glutamatergic afferents from the cortex. Under the hypothesis that basal ganglia perform action selection, these cortical afferents encode potential "action requests." Previous studies have suggested the striatum may utilize a mutually inhibitory network of medium spiny neurons (MSNs) to filter these requests so that only those of high salience are selected. However, the mechanisms enabling the striatum to perform clean, rapid switching between distinct actions that form part of a learned action sequence are still poorly understood. Substance P (SP) and enkephalin are neuropeptides co-released with GABA in MSNs preferentially expressing D

Indexed as

action selectionaction sequencebasal gangliachunkingenkephalinneuropeptidesstriatumsubstance P

Identifiers

PMID28798678
PMCPMC5529366
OpenAlexW2737231641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.