ArticleScientific reports2017
Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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Who cites it
35 citing papers in PubMed, 92 citations in OpenAlex.
- Widespread horizontal transfer and strong selection enhance microbial adaptation in Antarctic soils.Nature communications · 2026Article
- Single-cell transcriptomics reveals lateral transfers of multiple functional genes from prokaryotes to free-living ciliated protists in detrital food webs.Marine life science & technology · 2026Article
- Composition of the freshwater decapod crustacean communities in an area of mining in Brazilian Amazonia and the variation related to environmental parameters.Scientific reports · 2025Article
- Genetic and species rearrangements in microbial consortia impact biodegradation potential.The ISME journal · 2025Article
- Biosensor-aided isolation of anaerobic arsenic-methylating bacteria from soil.ISME communications · 2025Article
- Growth substrate limitation enhances anaerobic arsenic methylation byApplied and environmental microbiology · 2024Article
- Amphibian tolerance to arsenic: microbiome-mediated insights.Scientific reports · 2024Article
- Purifying selection drives distinctive arsenic metabolism pathways in prokaryotic and eukaryotic microbes.ISME communications · 2024Article
- Arsenic and Microorganisms: Genes, Molecular Mechanisms, and Recent Advances in Microbial Arsenic Bioremediation.Microorganisms · 2023Review
- Two-tiered mutualism improves survival and competitiveness of cross-feeding soil bacteria.The ISME journal · 2023Article
- Discovery of a novel bacterial class with the capacity to drive sulfur cycling and microbiome structure in a paleo-ocean analog.ISME communications · 2023Article
- Arsenite Methyltransferase Diversity and Optimization of Methylation Efficiency.Environmental science & technology · 2023Article
- In silico comparative structural and functional analysis of arsenite methyltransferase from bacteria, fungi, fishes, birds, and mammals.Journal, genetic engineering & biotechnology · 2023Article
- Navigating a Two-Way Street: Metal Toxicity and the Human Gut Microbiome.Environmental health perspectives · 2022Article
- Distribution and Evolutionary History of Sialic Acid Catabolism in the PhylumMicrobiology spectrum · 2022Article
- Organoarsenical tolerance in Sphingobacterium wenxiniae, a bacterium isolated from activated sludge.Environmental microbiology · 2022Article
- Functional characterization of the methylarsenite-inducible arsRM operon from Noviherbaspirillum denitrificans HC18.Environmental microbiology · 2022Article
- Volatile organic compounds shape belowground plant-fungi interactions.Frontiers in plant science · 2022Review
- Article
- ArsV and ArsW provide synergistic resistance to the antibiotic methylarsenite.Environmental microbiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
The toxic metalloid arsenic has been environmentally ubiquitous since life first arose nearly four billion years ago and presents a challenge for the survival of all living organisms. Its bioavailability has varied dramatically over the history of life on Earth. As life spread, biogeochemical and climate changes cyclically increased and decreased bioavailable arsenic. To elucidate the history of arsenic adaptation across the tree of life, we reconstructed the phylogeny of the arsM gene that encodes the As(III) S-adenosylmethionine (SAM) methyltransferase. Our results suggest that life successfully moved into arsenic-rich environments in the late Archean Eon and Proterozoic Eon, respectively, by the spread of arsM genes. The arsM genes of bacterial origin have been transferred to other kingdoms of life on at least six occasions, and the resulting domesticated arsM genes promoted adaptation to environmental arsenic. These results allow us to peer into the history of arsenic adaptation of life on our planet and imply that dissemination of genes encoding diverse adaptive functions to toxic chemicals permit adaptation to changes in concentrations of environmental toxins over evolutionary history.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.