Evidence map›Paper›PMID 28798327›Full record

ArticleScientific reports2017

Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging.

Roxanne Hachani, Martin A Birchall, Mark W Lowdell, Georgios Kasparis, Le D Tung, Bella B Manshian, Stefaan J Soenen, Willy Gsell, Uwe Himmelreich, Codi A Gharagouzloo and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Energetic Electron-Assisted Synthesis of Tailored Magnetite (FeNanomaterials (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Nanotechnology-Assisted Cell Tracking.Nanomaterials (Basel, Switzerland) · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Effects of Iron Oxide Nanoparticles (γ-FeInternational journal of molecular sciences · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Roxanne HachaniBiophysics Group, Department of Physics and Astronomy, University College London, Gower Street, London, WC1E 6BT, UK.
Martin A BirchallUniversity College London Ear Institute, 332 Gray's Inn Road, London, WC1X 8EE, UK.
Mark W LowdellDepartment of Haematology, Royal Free Hospital, University College London, London, NW3 2QG, UK.
Georgios KasparisBiophysics Group, Department of Physics and Astronomy, University College London, Gower Street, London, WC1E 6BT, UK.
Le D TungBiophysics Group, Department of Physics and Astronomy, University College London, Gower Street, London, WC1E 6BT, UK.
Bella B ManshianMoSAIC/Biomedical MRI Unit, Department of Imaging and Pathology, University of Leuven, B3000, Leuven, Belgium.
Stefaan J SoenenMoSAIC/Biomedical MRI Unit, Department of Imaging and Pathology, University of Leuven, B3000, Leuven, Belgium.
Willy GsellMoSAIC/Biomedical MRI Unit, Department of Imaging and Pathology, University of Leuven, B3000, Leuven, Belgium.
Uwe HimmelreichMoSAIC/Biomedical MRI Unit, Department of Imaging and Pathology, University of Leuven, B3000, Leuven, Belgium.
Codi A GharagouzlooGordon Centre for Medical Imaging, Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Srinivas SridharNanomedicine Science and Technology Centre, Northeastern University, Boston, Massachusetts, USA.
Nguyen T K ThanhBiophysics Group, Department of Physics and Astronomy, University College London, Gower Street, London, WC1E 6BT, UK. ntk.thanh@ucl.ac.uk.
University College London · GBKU Leuven · BENortheastern University · US

Funding

Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
NIBIB NIH HHS T32 EB013180
6 · The paper itself

Abstract

Stem cell tracking in cellular therapy and regenerative medicine is an urgent need, superparamagnetic iron oxide nanoparticles (IONPs) could be used as contrast agents in magnetic resonance imaging (MRI) that allows visualization of the implanted cells ensuring they reach the desired sites in vivo. Herein, we report the study of the interaction of 3,4-dihydroxyhydrocinnamic acid (DHCA) functionalized IONPs that have desirable properties for T

Indexed as

Cell ShapeCell SurvivalCell TrackingColorimetryContrast MediaFerric CompoundsHumansIntravital MicroscopyMagnetic Resonance ImagingMesenchymal Stem CellsMicroscopy, Electron, TransmissionMitochondriaNanoparticlesReactive Oxygen SpeciesStaining and LabelingContrast MediaFerric Compoundsferric oxideReactive Oxygen Species

Identifiers

PMID28798327
PMCPMC5552868
OpenAlexW2744281956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.