Evidence map›Paper›PMID 28798222›Full record

ArticleMolecular & cellular proteomics : MCP2017

An Integrated Approach to Explore Composition and Dynamics of Cholesterol-rich Membrane Microdomains in Sexual Stages of Malaria Parasite.

Federica Fratini, Carla Raggi, Gabriella Sferra, Cecilia Birago, Anna Sansone, Felicia Grasso, Chiara Currà, Anna Olivieri, Tomasino Pace, Stefania Mochi and 5 more

Abstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The role of cholesterol in invasion and growth of malaria parasites.Frontiers in cellular and infection microbiology · 2022
    Review
  6. Article
  7. Article
  8. A Comprehensive Gender-related Secretome ofMolecular & cellular proteomics : MCP · 2020
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Federica FratiniFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Carla Raggi§Istituto Superiore di Sanità, Dipartimento di Biologia Cellulare e Neuroscienze.
Gabriella SferraFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Cecilia BiragoFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Anna Sansone¶Consiglio Nazionale delle Ricerche, I.S.O.F. - Bio Free Radicals.
Felicia GrassoFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Chiara CurràFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Anna OlivieriFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Tomasino PaceFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Stefania MochiFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Leonardo PicciFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Carla Ferreri¶Consiglio Nazionale delle Ricerche, I.S.O.F. - Bio Free Radicals.
Antonella Di Biase‖Istituto Superiore di Sanità, Dipartimento di Sanità Pubblica Veterinaria e Alimentare.
Elisabetta PizziFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate.
Marta PonziFrom the ‡Istituto Superiore di Sanità, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate; marta.ponzi@iss.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane microdomains that include lipid rafts, are involved in key physiological and pathological processes and participate in the entry of endocellular pathogens. These assemblies, enriched in cholesterol and sphingolipids, form highly dynamic, liquid-ordered phases that can be separated from the bulk membranes thanks to their resistance to solubilization by nonionic detergents. To characterize complexity and dynamics of detergent-resistant membranes of sexual stages of the rodent malaria parasite

Indexed as

AnimalsCholesterolComputer SimulationDetergentsDisease Models, AnimalGametogenesisHumansLife Cycle StagesLipidsMalariaMembrane MicrodomainsMiceMice, Inbred BALB CPlasmodium bergheiProteomicsSphingolipidsCholesterolDetergentsLipidsSphingolipids

Identifiers

PMID28798222
PMCPMC5629265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.