ArticleAJNR. American journal of neuroradiology2017
Improved Detection of Anterior Circulation Occlusions: The "Delayed Vessel Sign" on Multiphase CT Angiography.
Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 40 citations in OpenAlex.
- Analysis of the baseline multiphase computed tomographic angiography findings to predict clinical outcomes in patients with middle cerebral artery M1 occlusion treated with mechanical thrombectomy.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- CT perfusion enhances accuracy of intracranial occlusion detection in acute stroke: effect of specialty and experience level.Neuroradiology · 2025Article
- Thrombus perviousness in acute ischemic stroke: a scoping review of methodology, predictive value, and future perspectives.Neuroradiology · 2025Article
- Time-variant and tissue-level collaterals predict postoperative neurological recovery and clinical outcomes of patients with endovascular thrombectomy.Quantitative imaging in medicine and surgery · 2025Article
- Optimizing Radiation Dose and Image Quality in Stroke CT Protocols: Proposed Diagnostic Reference Levels for Multiphase CT Angiography and Perfusion Imaging.Diagnostics (Basel, Switzerland) · 2024Article
- Analysis of the role of perfusion parameters in predicting rupture of brain arteriovenous malformations: a multi-center study.Scientific reports · 2024Article
- Spatial CT perfusion data helpful in automatically locating vessel occlusions for acute ischemic stroke patients.Frontiers in neurology · 2023Article
- Practice enhancements with FastStroke ColorViz analysis in acute ischemic stroke.Journal of clinical imaging science · 2022Review
- Effects of multiphase versus single-phase CT angiography for the detection of distal cerebral vessel occlusion.Emergency radiology · 2021Article
- Multiphase CT Angiography: A Useful Technique in Acute Stroke Imaging-Collaterals and Beyond.AJNR. American journal of neuroradiology · 2021Review
- CT Angiography in Evaluating Large-Vessel Occlusion in Acute Anterior Circulation Ischemic Stroke: Factors Associated with Diagnostic Error in Clinical Practice.AJNR. American journal of neuroradiology · 2020Article
- Imaging evaluation of acute ischemic stroke.The Journal of international medical research · 2020Article
- The Next Step in the Treatment of Stroke.Frontiers in neurology · 2020Review
- An acute stroke CT imaging algorithm incorporating automated perfusion analysis.Emergency radiology · 2019Article
- Thrombus Permeability on Dynamic CTA Predicts Good Outcome after Reperfusion Therapy.AJNR. American journal of neuroradiology · 2018Article
- Presence of multi-segment clot sign on dynamic CT angiography: a predictive imaging marker of recanalisation and good outcome in acute ischaemic stroke patients.European radiology · 2018Article
- "Delayed Pial Vessels" in Multiphase CT Angiography Aid in the Detection of Arterial Occlusion in Anterior Circulation.AJNR. American journal of neuroradiology · 2018Article
- Article
- Prediction of the Multisegment Clot Sign on Dynamic CT Angiography of Cardioembolic Stroke.AJNR. American journal of neuroradiology · 2018Article
- Subtraction multiphase CT angiography: A new technique for faster detection of intracranial arterial occlusions.European radiology · 2018Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeMultiphase CTA, a technique to dynamically assess the vasculature in acute ischemic stroke, was primarily developed to evaluate collateral filling. We have observed that it is also useful in identifying distal anterior circulation occlusions due to delayed anterior circulation opacification on multiphase CTA, an observation we term the "delayed vessel sign." We aimed to determine the usefulness of this sign by comparing multiphase CTA with single-phase CTA. MATERIALS AND
methodsAll 23 distal anterior circulation occlusions during a 2-year period were included. Ten M1-segment occlusions and 10 cases without a vessel occlusion were also included. All patients had follow-up imaging confirming the diagnosis. Initially, the noncontrast CT and first phase of the multiphase CTA study for each patient were blindly evaluated (2 neuroradiologists, 2 radiology trainees) for an anterior circulation occlusion. Readers' confidence, speed, and sensitivity of detection were recorded. Readers were then educated on the "delayed vessel sign," and each multiphase CTA study was re-examined for a vessel occlusion after at least 14 days.
resultsThere was significant improvement in the sensitivity of detection of distal anterior circulation vessel occlusions (
conclusionsThe delayed vessel sign is a reliable indicator of anterior circulation vessel occlusion, particularly in cases involving distal branches. Assessment of the later phases of multiphase CTA for the delayed vessel sign leads to a significant improvement in the speed and confidence of interpretation, compared with single-phase CTA.
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