ArticleAJNR. American journal of neuroradiology2017
Imaging Biomarkers for Adult Medulloblastomas: Genetic Entities May Be Identified by Their MR Imaging Radiophenotype.
Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Anything but Little: a Pictorial Review on Anatomy and Pathology of the Cerebellum.Clinical neuroradiology · 2023Review
- Review
- Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Multidisciplinary Management of Medulloblastoma: Consensus, Challenges, and Controversies.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Effects of different molecular subtypes and tumor biology on the prognosis of medulloblastoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23.Cancers · 2021Review
- Review
- Updates on Management of Adult Medulloblastoma.Current treatment options in oncology · 2019Review
- Nomograms based on preoperative multiparametric magnetic resonance imaging for prediction of molecular subgrouping in medulloblastoma: results from a radiogenomics study of 111 patients.Neuro-oncology · 2019Article
- Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Review
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe occurrence of medulloblastomas in adults is rare; nevertheless, these tumors can be subdivided into genetic and histologic entities each having distinct prognoses. This study aimed to identify MR imaging biomarkers to classify these entities and to uncover differences in MR imaging biomarkers identified in pediatric medulloblastomas. MATERIALS AND
methodsEligible preoperative MRIs from 28 patients (11 women; 22-53 years of age) of the Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults (NOA-7) cohort were assessed by 3 experienced neuroradiologists. Lesions and perifocal edema were volumetrized and multiparametrically evaluated for classic morphologic characteristics, location, hydrocephalus, and Chang criteria. To identify MR imaging biomarkers, we correlated genetic entities
resultsThere were 19
conclusionsMR imaging biomarkers can help distinguish histologic and genetic medulloblastoma entities in adults and appear to be different from those identified in children.
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Registered trials
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